Results 181 to 190 of about 80,331 (267)

A case of maturity‐onset diabetes of the young with a pathogenic HNF1A variant and a coexisting NEUROD1 variant

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Maturity‐onset diabetes of the young (MODY) accounts for at least 1%–5% of diabetes cases and is usually caused by single gene variants. Accurate diagnosis of MODY is important for effective management, especially in young individuals who are lean and lack islet autoantibodies.
Tomofumi Takayoshi   +9 more
wiley   +1 more source

Impact of Zinc‐Dependent Enzymes on Zinc Deficiency and Inflammatory Response in Ulcerative Colitis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Zinc (Zn) deficiency occurs in 40% of patients with ulcerative colitis (UC). Although Zn‐dependent enzymes are involved in intestinal immune regulation, their relationships with Zn deficiency and mucosal inflammation remain unclear.
Yuki Murakami   +7 more
wiley   +1 more source

AMD1-mediated polyamine metabolism governs tubular repair fate by restraining senescence after kidney injury. [PDF]

open access: yesRen Fail
Mao B   +9 more
europepmc   +1 more source

Clinical Prediction Models for Acute Kidney Injury in Neonatology—A Systematic Review and Modelling Analysis

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims Acute kidney injury (AKI) affects up to one‐third of neonates admitted to neonatal intensive care units (NICUs). NICUs are highly data‐rich environments, offering opportunities to develop clinical prediction rules (CPRs) that use clinical and demographic data to estimate AKI risk.
Dermot Wildes   +7 more
wiley   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai   +7 more
wiley   +1 more source

Prevalence, Comparative Risk, and Predictors of Shock in Children With Multisystem Inflammatory Syndrome Associated With COVID‐19: A Systematic Review and Meta‐Analysis

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Multisystem inflammatory syndrome in children (MIS‐C) is a severe hyperinflammatory condition associated with SARS‐CoV‐2 infection and is frequently complicated by cardiovascular dysfunction, particularly shock. Early recognition of shock in MIS‐C is critical to reduce morbidity and mortality.
Asif Jan   +6 more
wiley   +1 more source

Increased serum amyloid A and urinary kidney injury marker‐1 concentrations in cats with pyelonephritis: a diagnostic accuracy study

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To investigate the discriminatory potential of serum amyloid A, neutrophil:lymphocyte ratio, monocyte:lymphocyte ratio and assess renal tubular injury in cats with pyelonephritis. Materials and Methods Diagnostic accuracy study using samples from prospectively enrolled cats and stored material.
L. R. Jessen   +9 more
wiley   +1 more source

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