Results 91 to 100 of about 37,267 (288)

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer   +25 more
wiley   +1 more source

Structural relationship of κ-type light chains with AL amyloidosis: multiple deletions found in a VκIV protein [PDF]

open access: bronze, 1999
M A Alim   +7 more
openalex   +1 more source

Bilateral Chronic Subdural Nontraumatic Hematoma in a Woman Affected by AL Amyloidosis

open access: yesJournal of Neurological Surgery Reports, 2015
Chronic subdural hematoma (CSDH) is a condition frequently seen in neurosurgical practice, especially among the elderly. It is often preceded by head injury, even a trivial trauma. Light chain (AL) amyloidosis is a disorder involving extracellular tissue
M. Luongo, M. Grassi, U. Godano
doaj   +1 more source

Dose-Intensive Melphalan With Blood Stem-Cell Support for the Treatment of AL (Amyloid Light-Chain) Amyloidosis: Survival and Responses in 25 Patients [PDF]

open access: bronze, 1998
Raymond L. Comenzo   +13 more
openalex   +1 more source

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi   +19 more
wiley   +1 more source

Prospects for effective treatment of AL amyloidosis? [PDF]

open access: bronze, 2000
Neil Iggo   +2 more
openalex   +1 more source

Transthyretin amyloid cardiomyopathy in aortic stenosis patients scheduled for transcatheter aortic valve implantation

open access: yesESC Heart Failure, EarlyView.
Abbreviations: TAVI, transcatheter aortic valve implantation; ATTR‐CM, transthyretin cardiac amyloidosis. We aimed to diagnose occult ATTR‐CM in patients with severe aortic stenosis undergoing TAVI using bone scintigraphy. We verified a diagnosis of ATTR‐CM in 8 of 171 (4.7 %) consecutive aortic stenosis patients who underwent TAVI.
Margrethe Flesvig Holt   +15 more
wiley   +1 more source

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem   +13 more
wiley   +1 more source

SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper

open access: yesESC Heart Failure, EarlyView.
Abstract Background Sodium glucose co‐transporter 2 inhibitors (SGLT2i) and mineralocorticoid receptor antagonists (MRA) reduce heart failure (HF) events in patients with heart failure and mildly reduced or preserved ejection fraction (HFmr/pEF). The randomized comparison of SGLT2i/MRA combination versus SGLT2i or MRA alone requires further testing in ...
João Pedro Ferreira   +26 more
wiley   +1 more source

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