Results 111 to 120 of about 11,291,129 (270)

Autonomous Nanomedicine: Closing the Biological Validation Gap

Exploration, EarlyView.
Delivery of nanoparticles to tumors has not improved in over fifteen years, and biological testing remains slow and separate from formulation design. This review proposes adding a Biology step to the design cycle, using organ chips and patient‐derived organoids, and assesses the readiness of each required technology.
Yan Jun Lin, Izabella Komperda
wiley   +1 more source

Ascites revealing peritoneal amyloidosis and IgG kappa multiple myeloma: A case report

Radiology Case Reports
AL amyloidosis is a rare systemic disease characterized by the deposition of amyloid protein in various organs, including the kidneys, heart, peripheral nervous system, digestive tract, skin, and muscles.
Samia Sabri, Houda Bachir, Siham Hamaz, Habiba Alaoui Bennesser, Khalid Serraj   +4 more
doaj   +1 more source

Skeletal Muscle Pseudohypertrophy in AL Amyloidosis [PDF]

, 1997
A 65 year-old male presented a gastric ulcer, skeletal muscle firmness and pseudohypertrophy, macroglossia, monoclonal IgG-Kappa in the serum and monoclonal light chain of kappa type in the urine, with plasmacytosis in the marrow. A clinical diagnosis of
Dohi, Kazuko, Kitano, Norikazu, Isobe, Takashi, Miyawaki, Ikuko, Ishikawa, Hitoshi   +4 more
core  

Primary bladder amyloidosis as a cause of haematuria

, 2018
We report the case of a 46-year-old man who initially presented with macroscopic haematuria. Although initially concerning for a malignancy in the bladder, histology demonstrated a primary bladder amyloidosis that has remained stable for 6 years since ...
Nesbitt, AL, Khan, M, Lokan, J, Hoag, N
core   +1 more source

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source

Clinical and laboratory profile of renal amyloidosis: A single-center experience

Saudi Journal of Kidney Diseases and Transplantation, 2018
The kidney is the most common organ involved in systemic amyloidosis. We aimed to study etiology and clinicopathological profile of renal amyloidosis. This was a retrospective study of 40 consecutive adult patients with biopsy-proven renal amyloidosis ...
Divyesh P Engineer, Vivek B Kute, Himanshu V Patel, Pankaj R Shah   +3 more
doaj   +1 more source

Light chain type predicts organ involvement and survival in AL amyloidosis patients receiving stem cell transplantation

, 2018
Key Points λ Light chain AL amyloidosis is associated with a shorter PFS and OS compared with κ. Light chain type predicts likelihood of organ involvement in AL amyloidosis.
David Dingli, M Hasib Sidiqi, Angela Dispenzieri, Francis K. Buadi, Wilson I. Gonsalves, Prashant Kapoor, Taxiarchis V. Kourelis, Nelson Leung, Mohammed A. Aljama, Morie A. Gertz, Rahma Warsame, William J. Hogan, Shaji K. Kumar, Eli Muchtar, Martha Q. Lacy   +14 more
core   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy, Franziska Jochims, Manfred Kunz, Susann Forkel, Jan‐Christoph Simon, Benjamin Klein   +5 more
wiley   +1 more source

Current therapies for AL amyloidosis: literature review and our data

Клиническая онкогематология, 2013
AL amyloidosis is a relatively rare condition belonging to plasma cell dyscrasias with very heterogeneous clinical presentation and poor prognosis. This article presents a brief description of AL amyloidosis, current therapies, and our own statistics on ...
A. G. Smirnova, S. N. Bondarenko, A. A. Kisina, A. V. Smirnov, A. Tsander, B. V. Afanasyev   +5 more
doaj   +1 more source