Results 121 to 130 of about 54,210 (294)

Primary (AL) amyloidosis with gastrointestinal involvement

, 2009
Udgivelsesdato: 2009-nullOBJECTIVE: Immunoglobulin light-chain (AL) amyloidosis is a rare disease that can affect several organs. The aim of this study was to characterize patients with gastrointestinal manifestations of AL amyloidosis, in terms of ...
Madsen, Lone Galmstrup, Gimsing, Peter, Schiødt, Frank V   +2 more
core   +1 more source

Pre‐Imaging Clinical Factors Associated With Cardiac MR Image Quality Using Large Language Model‐Enabled Data Extraction

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Poor cardiac MR image quality can prompt repeat examinations and hinder clinical decision‐making. Purpose To evaluate whether pre‐imaging clinical information, extracted using a large language model (LLM), is independently associated with cardiac MR image quality. Study Type Retrospective.
Hong Yu, Masha Bondarenko, Ali Nowroozi, Yoo Jin Lee, Adrian Serapio, Punita Kaveti, Jae Ho Sohn   +6 more
wiley   +1 more source

Guidance for the assessment of the dietary intake and gastrointestinal or nutrition impact symptoms etiologic criterion of Global Leadership Initiative on Malnutrition: A modified‐Delphi study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The GLIM malnutrition diagnostic framework includes the etiologic criterion for reduced dietary intake or assimilation (i.e., digestion or absorption). This criterion required further specification to support consistent use in clinical practice.
Renée Blaauw, Heather Keller, Christine Marie Mills, Gert Bischoff, Charlene Compher, Marian de van der Schueren, Krista Haines, Nicole Kiss, Charles Lew, Ainsley Malone, Claudia Maza Moscoso, Nancy Stoner, Rocco Barazzoni, Jack J. Bell, Madeleine Coetzee, M. Isabel T. D. Correia, Ryoji Fukushima, Elena George, M. Cristina Gonzalez, Leah Gramlich, Yen Peng Lim, Roseann Nasser, Matthias Pirlich, Jacqueline A. E. Langius, Terese Scollard, Nicolette Wierdsma, Marion Winkler, Tommy Cederholm, Gordon L. Jensen   +28 more
wiley   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy, Franziska Jochims, Manfred Kunz, Susann Forkel, Jan‐Christoph Simon, Benjamin Klein   +5 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Epidemiology of Systemic Light-Chain (AL) Amyloidosis

Systemic light-chain (AL) amyloidosis is a challenging, complex and heterogeneous disease. AL amyloidosis is classified under the category of plasma cell neoplasms and other diseases with paraproteins in the fifth edition of the World Health Organization
Rafael Ríos-Tamayo
core   +1 more source

The Reliability of Intraoperative Frozen Section for Glottic Lesions Suspected of Early Malignancy

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Glottic lesions suspected of malignancy may be treated by laser cordectomy. Although obviating the preoperative biopsy can expedite treatment and preserve the surgical planes, it poses a risk of mistreatment. This study sought to determine if intraoperative frozen section (FS) prior to cordectomy can reliably guide lesion management.
Gal Levi, Yaniv Hamzany, Nir Tsur, Yulia Strenov, Daniel Ben‐Ner, Hagit Shoffel‐Havakuk   +5 more
wiley   +1 more source

Strategies to model AL amyloidosis in mice.

, 2011
International audienceMonoclonal immunoglobulin (Ig) deposition in AL amyloidosis is a severe complication of lymphoproliferative disorders. Research on this disease suffers from the lack of animal models, as they could allow for the testing of new ...
C. Sirac, G. Touchard, Bender, Sébastien, A. Jaccard, C. Lacombe, F. Bridoux, Jaccard, Arnaud, M. Cogné, Cogné, Michel, Sirac, Christophe, Bridoux, Franck, Lacombe, C., S. Bender, Touchard, G.   +13 more
core   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source