Results 131 to 140 of about 54,210 (294)
Rheumatology &Autoimmunity, EarlyView.Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen +6 more
wiley +1 more source
Management of the elderly patient with AL amyloidosis
, 2018 Systemic immunoglobulin light chain (AL) amyloidosis is an aging-associated protein misfolding and deposition disease. This condition is caused by a small and otherwise indolent plasma cell (or B cell) clone secreting an unstable circulating light chain,
Paolo Milani +7 more
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
SusMat, EarlyView.This article covers the basic theory and regulation strategies of amyloid‐like protein assembly, reviews the research progress of amyloid‐like protein assembly‐driven functional materials in light industry fields such as food, packaging, textiles, and biocatalysis, analyzes their sustainable advantages and challenges in these applications, and offers ...
Ruirui Liu +5 more
wiley +1 more source
Helical reconstruction of amyloids in cryoSPARC
Acta Crystallographica Section F, EarlyView.We present practical guidelines for helical reconstruction of amyloid filaments in cryoSPARC, benchmarked against publicly available datasets. Our analysis defines current capabilities and limitations, and outlines optimization strategies to enable high‐throughput structural studies and therapeutic discovery.Amyloid‐mediated proteotoxicity underlies ...
Jan-Hannes Schaefer +5 more
wiley +1 more source
Changrong Guan,1 Yonghua Liu,2 Riqiu Chen,1 Yingbiao Zhu3 1Department of Endocrinology, The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People’s Hospital, Lishui, Zhejiang, 323000, People’s ...
Liu Y, Zhu Y, Guan C, Chen R
core
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy
Acta Ophthalmologica, EarlyView.Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki +10 more
wiley +1 more source
Skeletal Muscle Pseudohypertrophy in AL Amyloidosis [PDF]
, 1997 A 65 year-old male presented a gastric ulcer, skeletal muscle firmness and pseudohypertrophy, macroglossia, monoclonal IgG-Kappa in the serum and monoclonal light chain of kappa type in the urine, with plasmacytosis in the marrow. A clinical diagnosis of
Dohi, Kazuko +4 more
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Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background Random skin biopsy (RSB) is a valuable method for diagnosis of intravascular lymphoma (IVL). Previous studies have performed RSB at multiple locations. This study aimed to evaluate the adequacy of a single RSB site and the appropriate depth of the biopsies for diagnosing IVL. Methods The study included 209 patients who underwent RSB
Phitsinee Purngpiputtrakul +6 more
wiley +1 more source
[Current treatment of AL amyloidosis].
, 2011 International audienceSystemic AL amyloidosis is a rare complication of monoclonal gammopathies. Renal manifestations are frequent, mostly characterized by heavy proteinuria, with nephrotic syndrome and renal failure in more than half of the patients at ...
Abraham, Julie +8 more
core +1 more source