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Immunoglobulin Light Chain Amyloidosis [PDF]
Clinical Case ReportsSymmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon +3 more
doaj +4 more sources
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to produce the amyloidogenic lights chains. They are able to misfold and aggregate, deposit in tissues in the form of amyloid fibrils and lead to irreversible organ ...
Paolo Milani +2 more
doaj +4 more sources
Diagnosis for Chinese patients with light chain amyloidosis: a scoping review
Annals of Medicine, 2023 Background Amyloid light chain (AL) amyloidosis is the most common systemic amyloidosis. The objective of this scoping review was to map the available literature on the diagnosis of AL amyloidosis in China.Materials and Methods The published academic ...
Meilan Chen +9 more
doaj +3 more sources
Hellenic Journal of Cardiology, 2019 Objective: Light-chain amyloidosis and transthyretin-related amyloidosis (wild-type and mutated) are three main types of systemic amyloidosis associated with a clinically relevant cardiac involvement. In this study, we compared prognosis in patients with
Yanguo Xin +5 more
doaj +3 more sources
An atypical cause of amyloidosis: a case of combined heavy and light chain amyloidosis [PDF]
BMC NephrologyBackground The International Society of Amyloidosis recognizes 15 types of kidney-related amyloidosis, with most studies identifying immunoglobulin light chain (AL) amyloidosis as the leading cause in over half of these cases.
Dina R. Gonzalez-Hernandez +2 more
doaj +2 more sources
Predicting survival in light chain amyloidosis
Haematologica, 2019 In this issue of the Journal, Dittrich and coworkers report their systematic analysis of the performance of the three currently used staging systems for AL amyloidosis in a large population of 1,224 patients.[1][1] Their aim was to establish whether one of the available models had ...
Giovanni Palladini +2 more
doaj +4 more sources
Strong positive light chain immunostaining in a patient with transthyretin amyloidosis
Hematology, 2023 The two most common systemic amyloidosis types are immunoglobulin light chain (AL) and amyloid transthyretin (ATTR) amyloidosis, in which the precursor proteins responsible for amyloidosis are light chain and transthyretin, respectively.
Jiao Chen +5 more
doaj +1 more source
Light-Chain Cardiac Amyloidosis
JACC: Case Reports, 2019 Gonzalo Barge-Caballero, MD +2 more
doaj +3 more sources
Amyloid light-chain deposition in a schwannoma
Interdisciplinary Neurosurgery, 2021 Systemic amyloid light-chain amyloidosis is a protein misfolding disorder characterized by extracellular deposition of amyloid fibrils derived from abnormal clonal immunoglobulin light chains in various organ systems.
Megan M. Jack +6 more
doaj +1 more source
A Case of Localized Amyloid Light-Chain Amyloidosis in the Small Intestine [PDF]
Intestinal Research, 2014 Amyloidosis is characterized by the abnormal deposition of extracellular amyloid fibrils. Cases involving amyloid light-chain amyloidosis in the small intestine have been reported infrequently in Korea.
Jong Hyo Choi +7 more
doaj +1 more source