Results 1 to 10 of about 20,644 (159)

Immunoglobulin Light Chain Amyloidosis [PDF]

Clinical Case Reports
Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon, Ashley Khouri, Katheryn A. Bell, Jamie Zussman   +3 more
doaj   +5 more sources

LIGHT CHAIN AMYLOIDOSIS [PDF]

Mediterranean Journal of Hematology and Infectious Diseases, 2018
Light chain (AL) amyloidosis is caused by a usually small plasma-cell clone that is able to produce the amyloidogenic lights chains. They are able to misfold and aggregate, deposit in tissues in the form of amyloid fibrils and lead to irreversible organ ...
Paolo Milani, Giampaolo Merlini, Giovanni Palladini   +2 more
doaj   +4 more sources

Light-Chain Cardiac Amyloidosis

JACC: Case Reports, 2019
[Figure: see text]
Gonzalo Barge-Caballero, MD, María G. Crespo-Leiro, PhD, Rafael C. Vidal-Pérez, PhD   +2 more
doaj   +4 more sources

An atypical cause of amyloidosis: a case of combined heavy and light chain amyloidosis [PDF]

BMC Nephrology
Background The International Society of Amyloidosis recognizes 15 types of kidney-related amyloidosis, with most studies identifying immunoglobulin light chain (AL) amyloidosis as the leading cause in over half of these cases.
Dina R. Gonzalez-Hernandez, Mohamad Hanouneh, C. Elena Cervantes   +2 more
doaj   +2 more sources

Systemic amyloid light-chain amyloidosis beyond ANDROMEDA: Diagnostic challenges and therapeutic updates. [PDF]

CA Cancer J Clin
Wu X, Landau H, Liu JE, Cao Y, Comenzo RL.   +4 more
europepmc   +2 more sources

Strong positive light chain immunostaining in a patient with transthyretin amyloidosis

Hematology, 2023
The two most common systemic amyloidosis types are immunoglobulin light chain (AL) and amyloid transthyretin (ATTR) amyloidosis, in which the precursor proteins responsible for amyloidosis are light chain and transthyretin, respectively.
Jiao Chen, Haifei Chen, Lingyun Zhou, Danbo Liu, Fang Du, Hongxian Xiang   +5 more
doaj   +1 more source

DUAL expectations in light chain amyloidosis [PDF]

EClinicalMedicine, 2020
Stefan Schönland, Giovanni Palladini
doaj   +4 more sources

Systemic immunoglobulin light chain amyloidosis [PDF]

Nature Reviews Disease Primers, 2018
Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by the conversion of immunoglobulin light chains from their soluble functional states into highly organized amyloid fibrillar aggregates that lead to organ dysfunction.
Merlini G., Dispenzieri A., Sanchorawala V., Schonland S. O., Palladini G., Hawkins P. N., Gertz M. A.   +6 more
openaire   +6 more sources

Amyloid light-chain deposition in a schwannoma

Interdisciplinary Neurosurgery, 2021
Systemic amyloid light-chain amyloidosis is a protein misfolding disorder characterized by extracellular deposition of amyloid fibrils derived from abnormal clonal immunoglobulin light chains in various organ systems.
Megan M. Jack, Brandon W. Smith, Christopher J. Klein, Taxiarchis Kourelis, Andrew L. Folpe, Robert J. Spinner, Ellen D. McPhail   +6 more
doaj   +1 more source

A Case of Localized Amyloid Light-Chain Amyloidosis in the Small Intestine [PDF]

Intestinal Research, 2014
Amyloidosis is characterized by the abnormal deposition of extracellular amyloid fibrils. Cases involving amyloid light-chain amyloidosis in the small intestine have been reported infrequently in Korea.
Jong Hyo Choi, Bong Min Ko, Cheol Kim, Hee Kyung Kim, Jae Pil Han, Su Jin Hong, Jong Ho Moon, Moon Sung Lee   +7 more
doaj   +1 more source