Results 21 to 30 of about 4,786,755 (237)
Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis
Dermatology Practical & Conceptual, 2018 We present a case of subcutaneous nodular amyloidosis mimicking a pilar cyst. Further evaluation led to the diagnosis of malignant systemic light-chain amyloidosis. The epidemiology and histopathological features of light-chain amyloidosis with cutaneous
Joseph Tadros +2 more
doaj +2 more sources
Update on treatment of light chain amyloidosis [PDF]
Haematologica, 2014 Light chain amyloidosis is the most common type of amyloidosis as a consequence of protein misfolding of aggregates composed of amyloid fibrils. The clinical features are dependent on the organs involved, typically cardiac, renal, hepatic, peripheral and autonomic neuropathy and soft tissue.
S. Mahmood +3 more
openaire +5 more sources
Blood Advances, 2018 : We evaluated the impact of light chain type, lambda (λ) or kappa (κ), on disease features and outcomes in patients with immunoglobulin light chain (AL) amyloidosis receiving stem cell transplant at the Mayo Clinic between October 2002 and August 2016 ...
M Hasib Sidiqi +14 more
doaj +2 more sources
Localized Lymph Node Light Chain Amyloidosis [PDF]
, 2020 The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light
Yamashita, Taro +4 more
core +2 more sources
Molecular pathogenesis and progression of light chain amyloidosis [PDF]
, 2022 Light chain amyloidosis is a malignant plasma cell disease characterized by the production and secretion of immunoglobulin light chains, aggregating as amyloid and causing end organ damage, most frequently in heart and kidney.
Beck, Susanne Monika
core +1 more source
Imaging Advances in Light Chain Amyloidosis. [PDF]
Diagnostics (Basel)Light chain (AL) amyloidosis is a systemic disorder caused by plasma cell dyscrasia, with cardiac involvement being the primary determinant of prognosis. Survival outcomes vary significantly across disease stages.
Qiu M, Shen K, Yang H, Wang J, Li J.
europepmc +2 more sources
Pseudoxanthoma Elasticum and Light-Chain Amyloidosis [PDF]
European Journal of Inflammation, 2012 Pseudoxanthoma elasticum is a heritable disorder of connective tissue characterized by cutaneous, vascular and ocular changes that result from the accumulation of fragmented elastic fibres. Even though the etiopathogenesis is not still completely understood, in recent years in literature some Authors have considered pseudoxanthoma elasticum as a ...
M. Carlesimo +8 more
openaire +2 more sources
PLoS ONE, 2020 Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. AL amyloidosis is caused by a misfolded light chain produced by a clonal population of plasma cells.
Elaine C Chen +9 more
doaj +1 more source
Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome [PDF]
, 2013 Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM +15 more
core +1 more source
BMC Nephrology, 2018 Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe +6 more
doaj +1 more source