Results 251 to 260 of about 17,175,483 (375)

Periorbital purpura of AL amyloidosis

Rheumatology, 2020
Michael Chen-Xu, Katerina Achilleos
openaire   +2 more sources

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source

Long-term outcome of patients with AL amyloidosis treated with high-dose melphalan and stem-cell transplantation

, 2007
Vaishali Sanchorawala, Martha Skinner, Karen Quillen, Kathleen T. Finn, Gheorghe Doros, David C. Seldin   +5 more
openalex   +1 more source

Predictive value of free light chain burden in patients with AL amyloidosis treated with bortezomib-based regimens. [PDF]

Blood Adv
Saunders B, Theodorakakou F, Fotiou D, Boullt S, Evans B, Dimopoulos MA, Kastritis E, Bianchi G.   +7 more
europepmc   +1 more source

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

Serum Visfatin Level and Cardiac Valve Calcifcation in Hemodialysis Patients

Hemodialysis International, EarlyView.
ABSTRACT Background Cardiac valve calcification is a serious complication in patients with cardiovascular disease. This study investigated the relationship between visfatin levels and cardiac valve calcification in individuals undergoing hemodialysis.
Xiaoqi Wang, Dan Yuan, Feng Shao, Conghui Liu, Xiao Zhang, Zhongxin Li   +5 more
wiley   +1 more source

Comparison of right ventricular longitudinal strain imaging, tricuspid annular plane systolic excursion, and cardiac biomarkers for early diagnosis of cardiac involvement and risk stratification in primary systematic (AL) amyloidosis: a 5-year cohort study [PDF]

, 2012
Diego Bellavia, Patricia A. Pellikka, Angela Dispenzieri, Christopher G. Scott, Ghormallah B. Al-Zahrani, Martha Grogan, Francesco Pitrolo, Jae K. Oh, Fletcher A. Miller   +8 more
openalex   +1 more source

Light Chain (AL) Amyloidosis Masquerading as Scleroderma: A Diagnostic Challenge. [PDF]

J Hematol
Dhamija K, Jiwani RA, Lakshaman A, Sadashiv S, Mewawalla P.   +4 more
europepmc   +1 more source

[Amyloidosis AL].

Haematologica, 1990
ASCARI, EDOARDO, BELLOTTI, VITTORIO, MERLINI, GIAMPAOLO, PERFETTI V, BUCCIARELLI E   +4 more
openaire   +1 more source

Elevation of Immunoglobulin Free Light Chain and BAFF Levels Associated With Immune Activation Predicts Survival Rates in Chronic Liver Disease

Hepatology Research, EarlyView.
ABSTRACT Aims Elevated serum free light chain (FLC) and B‐cell activating factor (BAFF) levels have been reported to be associated with B‐cell activation and to serve as biomarkers reflecting disease severity in various diseases. However, limited investigation has been conducted in the context of chronic liver disease (CLD), and the aim of this study ...
Motoh Iwasa, Akiko Eguchi, Yasuyuki Tamai, Ryuta Shigefuku, Hideaki Tanaka, Ryo Nakagawa, Mina Tempaku, Yoshinao Kobayashi, Hayato Nakagawa   +8 more
wiley   +1 more source