Results 331 to 340 of about 17,175,483 (375)

Feasibility of a Biomarker-Based Screening for Pre-Symptomatic AL Amyloidosis in Patients With Intermediate/High-Risk MGUS. [PDF]

Am J Hematol
Mangiacavalli S, Milani P, Cartia CS, Varettoni M, Palumbo M, Basset M, Masoni V, Nuvolone M, Foli A, Ferretti VV, Merlini G, Arcaini L, Palladini G.   +12 more
europepmc   +1 more source

Retinal microvascular alterations in Alzheimer's disease: Linking blood plasma biomarkers and cerebral small vessel pathology

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract BACKGROUND Retinal microvascular alterations, detectable via color fundus photography (CFP), may reflect cerebral microvascular pathology in Alzheimer's disease (AD). However, their associations with blood‐based biomarkers and cerebral small vessel disease (SVD) remain unclear.
William Robert Kwapong, Ning Wu, Weihong Lin, Jianing Shen, Youjie Wang, Jiajing Qian, Caiyun Wen, Xiaoqian Luan, Yuntao Liu, Haoran Cheng, Huihua Qiu, Carol Y. Cheung, Chunwen Zheng, Yinhe Liu, Yunjun Yang, Vincent Mok, Zhen Wang   +16 more
wiley   +1 more source

Defying the odds: 30 years in AL amyloidosis research-recent barriers to clinical trial enrollment. [PDF]

Blood Adv
Sanchorawala V, Barroso B, Shelton A, Goetz E, Mendelson L, Joshi T, Burke N, Sloan JM, Staron A.   +8 more
europepmc   +1 more source

Independent effects of white matter lesion volume and APOE ɛ4 on ARIA‐H in A4 Study

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Increased white matter hyperintensity (WMH) volume is a common but non‐specific finding in AD. This study investigates the effect of baseline WMH volume and APOE ε4 on magnetic resonance imaging (MRI)‐visible hemorrhagic lesion emergence.
Zahra Shirzadi, Aaron P. Schultz, Nazila Loghmani, Hyun‐Sik Yang, Jeremy Ford, Roy Yaari, Michael Properzi, Wai‐Ying W. Yau, Lei Liu, Michael S. Rafii, Michael C. Donohue, Adam M. Brickman, Clifford R. Jack Jr, Steven M. Greenberg, Paul Aisen, Reisa A. Sperling, Jasmeer P. Chhatwal, the A4 Study Team   +17 more
wiley   +1 more source

Daratumumab-based regimens versus CyBorD in newly diagnosed patients with AL amyloidosis and IIIb cardiac stage: A matched case-control study. [PDF]

Hemasphere
Bellofiore C, Basset M, Sanna GD, Foli A, Mussinelli R, Nanci M, Fogliani A, Ciardo M, Nuvolone M, Merlini G, Palladini G, Milani P.   +11 more
europepmc   +1 more source

Apolipoprotein ε4 exacerbates white matter impairment in a mouse model of Aβ amyloidosis by decreasing actively myelinating oligodendrocytes

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION The ε4 allele of the apolipoprotein E (APOE) gene is a risk factor for the development of Alzheimer's disease (AD). APOE4 isoform is associated with increased white matter lesions in humans. To identify the underlying mechanisms of white matter impairment associated with APOE4, we investigated the effects of APOE4 and APOE3 on ...
Md Mamun Al‐Amin, Byungwook Kim, Hande Karahan, Mason D. Tate, Sam P. Walsh, Shweta S. Puntambekar, Stephanie J. Bissel, Bruce T. Lamb, Nian Wang, Jungsu Kim   +9 more
wiley   +1 more source

Early dFLC response by C1D7 predicts complete hematologic response in systemic AL amyloidosis. [PDF]

Ann Hematol
Liu Y, Bi J, Dou X, Peng N, Wen L, Zhao Y, Huang X, Lu J.   +7 more
europepmc   +1 more source

Emerging therapeutics for the treatment of light chain and transthyretin amyloidosis [PDF]

, 2019
Lenihan, Daniel J, Stockerl-Goldstein, Keith E, Zhang, Kathleen W   +2 more
core   +1 more source

Combining plasma p‐tau231 and glial fibrillary acidic protein produces higher discriminative accuracy for amyloid positivity than other blood‐based biomarker combinations

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Plasma phosphorylated tau231 (p‐tau231) has shown great promise for early identification of amyloid pathology. We tested various plasma biomarker combinations with p‐tau231 in relation to cerebrospinal fluid (CSF) amyloid positivity. METHODS One hundred and fifty‐five dementia‐free older adults were included.
Corey J. Bolton, Omair A. Khan, Dandan Liu, Kimberly R. Pechman, Katherine A. Gifford, Timothy J. Hohman, Kaj Blennow, Henrik Zetterberg, Angela L. Jefferson   +8 more
wiley   +1 more source

Lung Transplantation for Pulmonary AL Amyloidosis. [PDF]

Transplant Direct
Ehrlich MI, Hughes MS, Labadie BW, Siegelin MD, D'Ovidio F, Bijou R, Lentzsch S, Arcasoy SM.   +7 more
europepmc   +1 more source