A possible role of myristoylated alanine-rich C kinase substrate in endocytic pathway of Alzheimer’s disease [PDF]
Rui Su +3 more
openalex +1 more source
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu +17 more
wiley +1 more source
Effects of Nutritional Supplements on Explosive Lower Limb Performance in Volleyball Players: A Systematic Review and Network Meta-Analysis. [PDF]
Du H +9 more
europepmc +1 more source
A single nucleotide polymorphism in the alcohol dehydrogenase 7 gene (alanine to glycine substitution at amino acid 92) is associated with the risk of squamous cell carcinoma of the head and neck [PDF]
Sheng Wei +7 more
openalex +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Electron and proton FLASH beam dosimetry using unified alanine, EBT-XD, and HD-V2 Gafchromic film dosimeters. [PDF]
Jung S +11 more
europepmc +1 more source
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source
Unveiling the phenylalanine coaggregation mechanism for a deep understanding of phenylketonuria disease. [PDF]
Barazorda-Ccahuana HL, Mas F, Madurga S.
europepmc +1 more source

