Results 201 to 210 of about 614,051 (372)

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

The homeostasis of β-alanine is key for Arabidopsis reproductive growth and development. [PDF]

open access: yesPlant J
Wu S   +12 more
europepmc   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

open access: yesAdvanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai   +5 more
wiley   +1 more source

Exploring Naproxen Cocrystals Through Solid-State Vibrational Circular Dichroism. [PDF]

open access: yesChirality
Sklenář A   +4 more
europepmc   +1 more source

Extracellular Vesicle‐Packaged Linc‐ZNF25‐1 from Pancreatic Cancer Cell Promotes Pancreatic Stellate Cell Uptake of Asparagine to Advance Chemoresistance

open access: yesAdvanced Science, EarlyView.
This study explores the role of gemcitabine (GEM)‐resistant pancreatic cancer‐derived extracellular vesicles (EVs) in activating pancreatic stellate cells (PSCs) and promoting extracellular matrix production. GEM‐resistant cells release higher levels of asparagine (Asn), which triggers PSC activation. Long noncoding RNA sequencing identified linc‐ZNF25‐
Miao Yu   +6 more
wiley   +1 more source

Role of metal(ii) hexacyanocobaltate(iii) surface chemistry for prebiotic peptides synthesis. [PDF]

open access: yesRSC Adv
Saroha B   +7 more
europepmc   +1 more source

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