THE FREE ENERGIES OF FORMATION OF AQUEOUS d-ALANINE, l-ASPARTIC ACID, AND d-GLUTAMIC ACID
Henry Borsook, Hugh M. Huffman
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Mitochondrial defects associated with β-alanine toxicity: relevance to hyper-beta-alaninemia
A. Shetewy+7 more
semanticscholar +1 more source
Using a 3D tumor microenvironment (TME)‐on‐a‐chip model, tumor–stromal–immune crosstalk in triple‐negative breast cancer is studied, revealing the TME's combinatorial effect on cancer progression. Integrating single‐cell transcriptomic analysis demonstrates metabolic reprogramming via the kynurenine pathway, highlighting the complex TME cellular ...
Kalpana Ravi+7 more
wiley +1 more source
Serum metabolomic profiling uncovered metabolic shifts in individuals upon moderate-altitude exposure and identified the potentiality of beta-alanine to ameliorate hyperuricemia. [PDF]
Chen X+14 more
europepmc +1 more source
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li+11 more
wiley +1 more source
Sport supplementation in competitive swimmers: a systematic review with meta-analysis. [PDF]
Domínguez R+6 more
europepmc +1 more source
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan+11 more
wiley +1 more source
Structural characterization reveals substrate recognition by the taurine transporter TauT. [PDF]
Xu H+10 more
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Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan+16 more
wiley +1 more source
Biosynthesis of a Novel Diketopiperazine Aspkyncin Incorporating a Kynurenine Unit from <i>Aspergillus aculeatus</i>. [PDF]
Kong D, Wang X, Liu L.
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