Results 231 to 240 of about 590,361 (310)

Lactate metabolism reprogramming through orthogonal tandem catalysis to reverse intervertebral disc degeneration. [PDF]

Nat Commun
Xia P, Zheng J, Han Z, Chen Y, Xu L, Yu J, Ye X, Cui W.   +7 more
europepmc   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Gender-specific association between AST/ALT ratio and 365-day mortality in patients with severe acute pancreatitis: A retrospective cohort study based on the MIMIC-IV database. [PDF]

Medicine (Baltimore)
Dong Z, Dang D.
europepmc   +1 more source

Toward Flexible Printed Electronics: A Spider‐Silk‐Inspired, Strong and Tough Thermoplastic Polyamide Elastomer

Advanced Science, EarlyView.
Inspired by spider silk, a bio‐inspired polyamide elastomer with a dynamic physical cross‐linking network is developed. Mimicking the rigid β‐sheet crystals and sacrificial hydrogen bonds of silk, the material achieves an exceptional balance of strength and toughness.
Bo Yang, Liyue Zhang, Mengjing Yang, Hangzhi Guo, Zhibo Lin, Xinyu Qi, Wenjun Li, Haiyan Yan, Meng Li, Yanhui Chen, Weixing Chen, Zhenguo Liu, Wei Huang   +12 more
wiley   +1 more source

The outcome of Infliximab induction in patients with severe ulcerative colitis may be related to intestinal microbiota. [PDF]

Front Microbiol
Chen J, Zhou Q, Cao X, Jin S, Wu Y, Ren T, Xu C, Chen H, Zhang H, Zhang Y, Liu J.   +10 more
europepmc   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

GerAB residues predicted to interact with water based on MD simulations mediate germinosome stability in <i>Bacillus subtilis</i> spores. [PDF]

Front Microbiol
Chen L, van Buuren S, Korza G, Vreede J, Setlow P, Brul S.   +5 more
europepmc   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrine in vivo

Frontiers in Pharmacology
Paul J. Fitzgerald
doaj   +1 more source

Results of a remote audit program of reference and non-reference dosimetry of photon beams using alanine detectors. [PDF]

Phys Imaging Radiat Oncol
Yalvac B, Reulens N, Reniers B.
europepmc   +1 more source