Results 161 to 170 of about 457,916 (395)

Photoelectron Circular Dichroism of Aqueous-Phase Alanine [PDF]

open access: yesarXiv
Amino acids and other small chiral molecules play key roles in biochemistry. However, in order to understand how these molecules behave in vivo, it is necessary to study them under aqueous-phase conditions. Photoelectron circular dichroism (PECD) has emerged as an extremely sensitive probe of chiral molecules, but its suitability for application to ...
arxiv  

Arrow of time and non-Markovianity in the non equilibrium folding/unfolding of alanine decapeptide in vacuo [PDF]

open access: yesarXiv, 2009
We present non equilibrium molecular dynamics experiments of the unfolding and refolding of an alanine decapeptide in vacuo subject to a Nose-Hoover thermostat. Forward (unfolding) and reverse (refolding) work distribution are numerically calculated for various duration times of the non equilibrium experiments. Crooks theorem is accurately verified for
arxiv  

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

The Study of 201TlCl Short-Term Effects on Rat Serum Factors [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2011
Tl-201 administration for cardial scan using SPECT has been performed for more than 4 decades, while in Iran it has been produced and used for 17 years.
A.R Jalilian, M Alinejad
doaj  

Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species [PDF]

open access: green, 1978
T. Noguchi   +5 more
openalex   +1 more source

Communications Among Neurocytes in Parkinson's Disease Regulated by Differential Metabolism and Blood‐Brain Barrier Traversing of Chiral Gold Cluster‐MOF Integrated Nanoparticles

open access: yesAdvanced Science, EarlyView.
This study have loaded chiral gold nanoclusters onto the inner and outer surfaces of ZIF and uncovers the biodistribution, metabolic variances, and therapeutic mechanism of chiral nanoparticles, providing deep insights into the nanobiological effects of chiral anti‐inflammatory nanomedicines in PD therapy for future clinical transformation.
Junyang Chen   +7 more
wiley   +1 more source

Serum alanine aminotransferase flares in chronic hepatitis B infection: the good and the bad.

open access: yesThe Lancet Gastroenterology and Hepatology, 2020
M. Ghany   +6 more
semanticscholar   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu   +10 more
wiley   +1 more source

Physical activity and elevated liver enzymes: A cross-sectional study from the PERSIAN Guilan cohort study [PDF]

open access: yesCaspian Journal of Internal Medicine
Background: Regular physical activity promotes health that can affect liver health, particularly modulating liver enzymes. The objective of this study was to assess the association between physical activities and elevated liver enzyme levels in the ...
Heydar Ali Balou   +5 more
doaj  

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