Results 161 to 170 of about 464,951 (372)

An enzyme trafficking defect in two patients with primary hyperoxaluria type 1: peroxisomal alanine/glyoxylate aminotransferase rerouted to mitochondria. [PDF]

, 1989
Christopher J. Danpure, P. J. Cooper, P. J. Wise, Patricia R. Jennings   +3 more
openalex   +1 more source

Nevirapine-Induced Heratotoxicity: Incidence, Risk Factors and Associated Mortality in a Primary Care ART Programme in South Africa [PDF]

, 2009
CROI ...
Abrahams, M, Boulle, A, Chu, K, Ford, N, Goemaere, E, Hilderbrand, K, Mathee, S   +6 more
core   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Elevated ALT/AST ratio as a marker for NAFLD risk and severity: insights from a cross-sectional analysis in the United States

Frontiers in Endocrinology
BackgroundThe prevalence and incidence of Nonalcoholic fatty liver disease (NAFLD) are increasing worldwide, and NAFLD has emerged as a prominent global health concern.
Yanyan Xuan, Yanyan Xuan, Yanyan Xuan, Dingting Wu, Qin Zhang, Zhiqiang Yu, Jingbo Yu, Dongdong Zhou   +7 more
doaj   +1 more source

Crystallization and characterization of human liver kynurenine–glyoxylate aminotransferase. Identity with alanine–glyoxylate aminotransferase and serine–pyruvate aminotransferase [PDF]

, 1980
Etsuo Okuno, Yohsuke Minatogawa, Masayuki Nakamura, Naoki Kamoda, Junko Nakanishi, Minoru Makino, Ryo Kido   +6 more
openalex   +1 more source

Alanine Aminotransferase Level: The Road to Normal in 2021 [PDF]

Hepatology Communications, 2021
Terry Cheuk‐Fung Yip, Vincent Wai‐Sun Wong, Grace Lai‐Hung Wong   +2 more
openaire   +4 more sources

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Reflotron assays of alanine aminotransferase and gamma-glutamyltransferase in whole-blood samples evaluated. [PDF]

, 1987
D.R. James, C P Price
openalex   +1 more source

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

Acute Effects of on Javdar Supplementation on Asparate Aminotransferase(AST) and Alanine Aminotransferase(ALT) after Exhaustive Incremental Exercise in Men’s Handball [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: The aim of this study was to investigate the acute effect of supplementation Jadvar on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzymes after exhaustive incremental exercise in men's handball. Materials and Methods:
Mojtaba Khansooz, Bahram Abedi, Mehdi Moradi, Abbas Mehranpour   +3 more
doaj