Results 161 to 170 of about 469,247 (341)

Serum levels of aminotransferase aspartate (AST), aminotransferase alanine (ALT) and creatinine evaluated in male Balb/c mice after application of a single dose of LMM5 and LMM11.

open access: yes, 2019
Serum levels of aminotransferase aspartate (AST), aminotransferase alanine (ALT) and creatinine evaluated in male Balb/c mice after application of a single dose of LMM5 and LMM11.
Maria Sueli Felipe (199245)   +11 more
core   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Influence of pyridoxalisonicotinoyl hydrazone on spectral properties of alanine aminotransferase

open access: yes, 2008
The aim of this study was to examine the influence of pyridoxalisonicotinoylhydrazone (PIH) on alanine aminotransferase (EC 2. 6. 1. 2.). Alanine aminotransferase belongs to the group of pyridoxal enzymes.
Vančurová, Kamila
core  

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

open access: yesAdvanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu   +12 more
wiley   +1 more source

An assay for L-alanine-glyoxylate aminotransferase [PDF]

open access: yesBiochemical Journal, 1969
E V, Rowsell, J A, Carnie, K, Snell
openaire   +2 more sources

New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, γ‐glutamyltransferase): Effects of age, sex, body mass index, and pubertal stage

open access: yesHepatology, 2018
Sarah Bussler   +10 more
semanticscholar   +1 more source

Plasma zinc concentrations had negative correlations with aspartate and alanine aminotransferase values.

open access: yes, 2013
Plasma zinc concentrations had negative correlations with aspartate and alanine aminotransferase values.
Rassamee Sangthong (424109)   +3 more
core   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Low Alanine Aminotransferase Levels in the Elderly Population: Frailty, Disability, Sarcopenia, and Reduced Survival

open access: yesThe journals of gerontology. Series A, Biological sciences and medical sciences, 2018
U. Vespasiani‐Gentilucci   +5 more
semanticscholar   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

open access: yesAdvanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim   +8 more
wiley   +1 more source

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