This study sought to determine the prevalence of significant liver disease in those subjects with serum alanine aminotransferase levels in the range between the current and the newly suggested upper limit of normal (termed the delta range).
Hemda Schmilovitz-Weiss +8 more
doaj +1 more source
Objective: Studies on the association of the aspartate transaminase-to-alanine transaminase ratio with the metabolic syndrome and its components among HIV patients were scarce.
Wondwossen Abera +2 more
doaj +1 more source
Additive effect of non-alcoholic fatty liver disease on metabolic syndrome-related endothelial dysfunction in hypertensive patients [PDF]
Metabolic syndrome (MS) is characterized by an increased risk of incident diabetes and cardiovascular (CV) events, identifying insulin resistance (IR) and endothelial dysfunction as key elements.
Caroleo, B +6 more
core +3 more sources
Physical activity is prospectively associated with adolescent nonalcoholic fatty liver disease [PDF]
Objectives: The aim of the present study was to assess whether objectively measured physical activity at mean ages 12 and 14 years are prospectively associated with ultrasound scan liver fat and stiffness (alanine aminotransferase, aspartate ...
Anderson, Emma L. +7 more
core +2 more sources
Objectives Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), yet the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to: 1) identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Protective Effect of Physalis Angulata Extract on Cisplatin-induced Hepatotoxicity in Rats
The Physalis angulata extract has various therapeutic potentials and antioxidant properties, making it a promising candidate in supportive therapies to reduce the side effects of cytotoxic drugs. This study aimed the protective effects of P.
Atyaf Salih Hamood, +2 more
doaj +1 more source
Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]
Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth +6 more
core +1 more source
Shaping Ti3C2 MXene Nanospheres for Precision Near‐Infrared Photothermal Therapy
In this study, we report producing spherical MXenes via fs laser fragmentation of Ti3C2 flakes in liquid medium. The nanoparticles demonstrated pronounced light absorption and high photothermal conversion efficiencies of 68% and 63% under heating with NIR‐I and NIR‐II lasers, respectively.
Julia S. Babkova +21 more
wiley +1 more source
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Badenhoop, Klaus +20 more
core +4 more sources
Comparison of Risk of Recrudescent Fever in Children With Kawasaki Disease Treated With Intravenous Immunoglobulin and Low-Dose vs High-Dose Aspirin [PDF]
Importance: Timely initiation of intravenous immunoglobulin plus aspirin is necessary for decreasing the risk of recrudescent fever and coronary artery abnormalities in children with Kawasaki disease (KD). The optimal dose of aspirin, however, remains
Belarski, Emily +6 more
core +1 more source

