Background: The pathogenic risk caused by the Leishmania donovani (L. donovani) parasite has long been known, and it has become necessary to find a suitable treatment other than traditional medications and their many side effects, among the best ...
Zahraa A. Ali, Hadeel A. Majeed
doaj +2 more sources
Metabolic Factors Associated with Alanine Transaminase Levels in Non-Alcoholic Fatty Liver Disease
Background: Non-Alcoholic Fatty Liver Disease is the most increasing chronic liver condition with a global prevalence of 30%. Metabolic factors like Obesity, Diabetes Mellitus are considered as major risk factors.
Safwa Mahmood +5 more
doaj
Association of Beverage Consumption with Cardio-metabolic Risk Factors and Alanine Transaminase Levels in Children and Adolescents: The CASPIAN-V Study. [PDF]
Khademian M +8 more
europepmc +1 more source
[Discussion regarding the reduction of the alanine transaminase threshold value in patients with chronic hepatitis B virus infection undergoing antiviral therapy]. [PDF]
Du YN, Cai W.
europepmc +1 more source
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source
Elevated Alanine Transaminase-to-Platelet Index (APRI) Is Associated with Obesity and Distinct Forms of Dyslipidemia: A Retrospective Cross-Sectional Study. [PDF]
Alshuweishi Y +7 more
europepmc +1 more source
A Cascaded DNA Nanocircuit for Multi‐Signal‐Responsive Precision siRNA Delivery in Cancer Therapy
A cascaded dual‐AND logic DNA nanocircuit is engineered to respond to three tumor‐specific signals in a sequential manner: extracellular acidic pH, membrane‐overexpressed nucleolin (NCL), and intracellular glutathione (GSH). This programmable system selectively releases siPARP1 in glioblastoma (GBM), effectively silencing PARP1 and reversing TMZ ...
Yan Zhao +14 more
wiley +1 more source
Lower HBV DNA level is associated with more severe liver fibrosis in HBeAg-positive chronic hepatitis B with normal alanine transaminase. [PDF]
Wang J +18 more
europepmc +1 more source
[Hepatic pathological characteristics and factors influencing alanine transaminase value below twice the upper limit of normal in patients with chronic hepatitis B]. [PDF]
Wang XH, Liu XQ, Cai DC, Hu P, Li H.
europepmc +1 more source
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source

