Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source
Association of Beverage Consumption with Cardio-metabolic Risk Factors and Alanine Transaminase Levels in Children and Adolescents: The CASPIAN-V Study. [PDF]
Khademian M +8 more
europepmc +1 more source
Extremely Low Serum Alanine Transaminase Level Is Associated with All-Cause Mortality in the Elderly after Intracranial Hemorrhage. [PDF]
Kim DY, Cho KC.
europepmc +1 more source
d-Alanine-d-Glutamate Transaminase
M. Martinez-Carrion, W. Terry Jenkins
openaire +1 more source
Glutamic–alanine and glutamic–aspartic transaminases of wheat germ [PDF]
D H, CRUICKSHANK, F A, ISHERWOOD
openaire +2 more sources
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang +15 more
wiley +1 more source
Background: The pathogenic risk caused by the Leishmania donovani (L. donovani) parasite has long been known, and it has become necessary to find a suitable treatment other than traditional medications and their many side effects, among the best ...
Zahraa A. Ali, Hadeel A. Majeed
doaj +2 more sources
Elevated Alanine Transaminase-to-Platelet Index (APRI) Is Associated with Obesity and Distinct Forms of Dyslipidemia: A Retrospective Cross-Sectional Study. [PDF]
Alshuweishi Y +7 more
europepmc +1 more source
[Hepatic pathological characteristics and factors influencing alanine transaminase value below twice the upper limit of normal in patients with chronic hepatitis B]. [PDF]
Wang XH, Liu XQ, Cai DC, Hu P, Li H.
europepmc +1 more source
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source

