De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase) as a Significant Prognostic Factor in Patients Undergoing Radical Cystectomy with Bladder Urothelial Carcinoma: A Propensity Score-Matched Study. [PDF]
Dis Markers, 2019 Introduction To investigate the correlation between preoperative De Ritis ratio (aspartate transaminase (AST)/alanine transaminase (ALT)) and postoperative outcome in patients with urothelial cell carcinoma (UC) treated with radical cystectomy. Materials
Yuk HD, Jeong CW, Kwak C, Kim HH, Ku JH.
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Improved Performance of Serum Alpha-Fetoprotein for Hepatocellular Carcinoma Diagnosis in HCV Cirrhosis with Normal Alanine Transaminase. [PDF]
Cancer Epidemiol Biomarkers Prev, 2017 Yang JD +14 more
europepmc +3 more sources
UC Davis - Alanine transaminase v1 [PDF]
protocols.io, 2019 Summary: Alanine transaminase (ALT) also known as alanine aminotransferase or (sGPT) is a metabolic enzyme expressed primarily in the liver. Elevation of ALT levels is an indication of liver damage and has been associated with liver injury. ALT levels are monitored routinely in patients with liver diseases.
Peter Havel
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Probing alanine transaminase catalysis with hyperpolarized 13CD3-pyruvate [PDF]
Journal of Magnetic Resonance, 2013 Hyperpolarized metabolites offer a tremendous sensitivity advantage (>10(4) fold) when measuring flux and enzyme activity in living tissues by magnetic resonance methods. These sensitivity gains can also be applied to mechanistic studies that impose time and metabolite concentration limitations.
John Glushka +3 more
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Porcine alanine transaminase after liver allo‐and xenotransplantation [PDF]
Xenotransplantation, 2012 Ekser B, Gridelli B, Cooper DKC. Porcine alanine transaminase after liver allo‐ and xenotransplantation. Xenotransplantation 2012; 19: 52–55. © 2012 John Wiley & Sons A/S.Abstract: Aspartate transaminase (AST) and alanine transaminase (ALT) are measured following liver transplantation as indicators of hepatocellular injury.
David K. C. Cooper +2 more
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Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. [PDF]
Cell Rep, 2022 Martino MR +16 more
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Alanine Transaminase Level in a Healthy Population in Morocco
Pakistan Journal of Biological Sciences, 2012 A little is known about the prevalence of elevated alanine transaminase in a Moroccan healthy population. Our aim was to search for the upper limit of normal alanine transaminase in the blood donors and then to apply the upper limit of normal alanine found in the population so as to assess the prevalence of subjects with abnormal transaminase level. We
R. Alami +3 more
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Characterization of T cell immunity in chronic hepatitis B virus-infected mothers with postpartum alanine transaminase flare. [PDF]
BMC Infect Dis, 2021 Background Postpartum alanine transaminase (ALT) flares occur frequently in chronic hepatitis B virus (HBV)-infected mothers with antepartum antiviral therapy (AVT).
Huang M +6 more
europepmc +2 more sources
Serum Alanine Transaminase Total Bilirubin Concentrations Predict CYP3A Activity as Measured by Midazolam and 1’-Hydroxylation [PDF]
Medical Science Monitor, 2015 Background Microsomal enzyme P450 (CYP450) plays an important role in metabolism of most xenobiotics. The activity of CYP3A decreases in patients with liver dysfunction. However, whether serum concentrations of liver enzymes reflect the activity of CYP3A
Jinguang Ruan
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Association of Alanine Transaminase and Aspartate Aminotransferase/Alanine Transaminase Ratio with Type 2 Diabetes and Metabolic Syndrome in the Elderly [PDF]
Zhongguo quanke yixue, 2023 Background Serum alanine transaminase (ALT) and aspartate aminotransferase (AST) are common liver enzymes, but there are few studies on the correlation of these enzymes with the prevalence of type 2 diabetes mellitus (T2DM) and metabolic syndrome (MS ...
ZHOU Xiaoqi, LIU Xinhui, ZHANG Wei, LI Changfeng, YAN Yaqiong
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