Results 221 to 230 of about 196,626 (324)

<p>High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center</p>

, 2019
Yifan Li, Dong Fang, Zhengqing Bao, Anbang He, Bao Guan, Shiming He, Yonghao Zhan, Yanqing Gong, Xuesong Li, Liqun Zhou   +9 more
openalex   +2 more sources

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

Nucleos(t)ide analogs to treat patients with positive hepatitis B virus deoxyribonucleic acid and normal alanine transaminase: protocol for an open-label single-center randomized parallel controlled trial. [PDF]

Trials
Zhou J, Wang FD, Li LQ, Li YJ, Wang SY, Chen EQ.   +5 more
europepmc   +1 more source

A β-Alanine Catabolism Pathway Containing a Highly Promiscuous ω-Transaminase in the 12-Aminododecanate-Degrading Pseudomonas sp. Strain AAC [PDF]

, 2016
Matthew Wilding, Thomas S. Peat, Janet Newman, Colin Scott   +3 more
openalex   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

High immunocompetence in chronic hepatitis patients with normal alanine transaminase levels and and negative hepatitis B e-antigen for the progression of liver fibrosis. [PDF]

Immun Inflamm Dis
Cheng B, Wu D, Zhang M, Chen S, Wu X, Zhong J, Wu M, Huo M.   +7 more
europepmc   +1 more source

Estimation of Upper Limit of Normal for Serum Alanine Transaminase in Healthy South Indian Population [PDF]

, 2016
Pazhanivel Mohan, Varun Sundar, Emmanuel Bhaskar, Syluvai Anthony   +3 more
openalex   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

The Role of Thrombocyte/Lymphocyte Ratio and Aspartate Transaminase/Alanine Transaminase (De Ritis) Ratio in Prediction of Recurrence and Progression in Non-muscle Invasive Bladder Cancer. [PDF]

Cureus
Avcı MA, Arslan B, Arslan O, Özdemir E.   +3 more
europepmc   +1 more source

PP-111 Optimal threshold: baseline serum hepatitis B virus DNA and alanine transaminase levels predict the 2-year on-treatment virological response to lamivudine

, 2010
Jingya Yan, Wen Xie, Q. Wang, Y. Li, X. Feng, Jun Cheng   +5 more
openalex   +1 more source