Results 131 to 140 of about 632,185 (263)

Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts

open access: yesAdvanced Science, EarlyView.
Cellular senescence contributes to disease burden in cardiovascular disease (CVD) and aging, highlighting the need to understand its induction. In primary cardiac fibroblasts, reduced strain and increased frequency, mimicking CVD, elicit a distinct senescent phenotype compared to oxidative stress.
Stephanie E. Schneider   +5 more
wiley   +1 more source

Invasive Group B Streptococcal Disease Among Nonpregnant Adults: Alaska, 2004-2023. [PDF]

open access: yesJ Infect Dis
Balta VA   +9 more
europepmc   +1 more source

Phenylboronic Acid‐Modified Copper Nanozymes as Nanoscavengers of Bacterial Polysaccharides Causing Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
A novel copper nanocluster coated with 4‐mercaptobenzeneboronic acid (CuMPBA) is developed to target bacterial polysaccharides for addressing complicated acute lung injury (ALI) caused by severe burns and early pulmonary infections. CuMPBA exhibits dual anti‐inflammatory and antibacterial mechanisms by: (a) binding and degrading toxic bacterial ...
Haojie Ge   +4 more
wiley   +1 more source

Bridging Knowledge Systems and Perspectives to Inform Salmon Management and Research: A Kuskokwim River Case Study. [PDF]

open access: yesEcol Evol
Esquible J   +12 more
europepmc   +1 more source

Precision Targeting of Myeloid Cells via Peptide Dendrimer‐Lipid Nanocarriers: A Novel Platform for Potent Cancer Immunotherapies

open access: yesAdvanced Science, EarlyView.
Precision targeting of the spleen and myeloid cells of the tumor microenvironment, with minimal hepatic delivery, is achieved using a modular peptide dendrimer‐lipid nanocarrier. Functional assays, transcriptomics, and rodent models validate this novel myeloid cell targeting nanocarrier as an efficacious immunotherapy, both as a cancer vaccine platform
Lawrence James Billing   +9 more
wiley   +1 more source

Elimination of Hepatitis B virus transmission in an endemic area in Western Alaska. [PDF]

open access: yesIJID Reg
McMahon BJ   +7 more
europepmc   +1 more source

Multicharged Zwitterions form Superior Antifouling Interfaces

open access: yesAdvanced Science, EarlyView.
Bolaamphiphilic multicharged sulfobetaine zwitterion forms self‐assembled monolayer for antifouling applications and vesicular aggregates for drug delivery applications. Abstract The long‐term prevention of unwanted protein and microbial accumulation on surfaces, including medical devices, remains a significant and largely unresolved challenge. Decades
Declan Meehan   +6 more
wiley   +1 more source

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