Results 31 to 40 of about 216,635 (309)
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The decline of aerial insectivorous birds has been hypothesized to stem, in part, from a decline in aerial arthropod prey, underscoring the need for long-term monitoring of both bird and arthropod populations.
Adam Haberski +4 more
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Alaskan English: Сontexts and conditions of emergence
Alaskan English (AE), or the regional variety of English used by Native Alaskans, is a unique yet largely underinvestigated phenomenon. Specific conditions in which Alaskan English and its distinct characteristics have emerged remain significantly ...
Anastasia A. Grigoryeva +1 more
doaj +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Alaskan wild food harvester information needs and climate adaptation strategies
Changing biophysical conditions due to amplified climate change in northern latitudes has significant implications for species' habitat and populations and can dramatically alter interactions between harvesters and local resources.
Casey L. Brown +3 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
A Study of the History of the Russian Orthodox Church in America, 1867–1917
Review of the monograph: Pechatnov V.O., Pechatnov V.V. 2025. The Russian Orthodox Church in America: Essays on History, 1867–1917. Moscow: Aspect Press. 448 p.
A. Yu. Petrov
doaj +1 more source

