Results 51 to 60 of about 179,880 (310)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

RESPONSE of TOW POTATO CULTIVARS TO HUMIC ACID FERTILIZER [PDF]

open access: yesMesopotamia Journal of Agriculture, 2018
This study was carried out at vegetables field of Horticulture and landscape department, College of Agriculture and Forestry, Mosul University, Iraq., during spring season 2013, to investigate the effect of Humic Acid addition in three concentrations (0,
Fathel Ibraheem
doaj   +1 more source

About Russian Alaska and Its Ruler A.A. Baranov

open access: yesАрктика и Север, 2021
The purpose of this study is to analyze the present and past of the history of Alaska. Such a combination of times highlighted the most difficult problem of ambiguous attitude to the historical past in the USA from the standpoint of modernity.
Yury F. LUKIN
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A Study of the History of the Russian Orthodox Church in America, 1867–1917

open access: yesVestnik MGIMO-Universiteta
Review of the monograph: Pechatnov V.O., Pechatnov V.V. 2025. The Russian Orthodox Church in America: Essays on History, 1867–1917. Moscow: Aspect Press. 448 p.
A. Yu. Petrov
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

The last deglaciation of Alaska

open access: yesCuadernos de Investigación Geográfica, 2017
We review available chronologies that constrain the timing of glacier fluctuations during the last deglaciation in Alaska. We address three questions relating to the last glacial termination: (i) How did the timing of glacier recession relate to buildup ...
J.P. Briner   +5 more
doaj   +1 more source

Rapid detection of tuberculosis in remote Alaska

open access: yesInternational Journal of Circumpolar Health, 2020
In a remote region of western Alaska where tuberculosis (TB) incidence remains relatively high, a rapid molecular detection assay (Xpert MTB/RIF) was introduced four years ago with goal of improving the ability to diagnose active pulmonary tuberculosis ...
Ronald J. Bowerman
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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