Assessment of efficacy and quality of two albendazole brands commonly used against soil-transmitted helminth infections in school children in Jimma Town, Ethiopia [PDF]
, 2015 Background : There is a worldwide upscale in mass drug administration (MDA) programs to control the morbidity caused by soil-transmitted helminths (STHs): Ascaris lumbricoides, Trichuris trichiura and hookworm. Although anthelminthic drugs which are used
D'Hondt, Matthias +11 more
core +32 more sources
Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer. [PDF]
, 2017 Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown.
Barrett, John W +17 more
core +1 more source
Peroxide impact on the fate of veterinary drugs in fertilizers [PDF]
, 2020 The presence of veterinary medicines in organic manure causes soil contamination which contributes to increasing resistance of indigenous microflora to drugs and results in greater susceptibility of people to allergies.
Kalka, Joanna +3 more
core +1 more source
A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia. [PDF]
PLoS Pathogens, 2012 Wolbachia endosymbionts carried by filarial nematodes give rise to the neglected diseases African river blindness and lymphatic filariasis afflicting millions worldwide.
Laura R Serbus +7 more
doaj +1 more source
Misoprostol in the management of the third stage of labour in the home delivery setting in rural Gambia: a randomised controlled trial. [PDF]
, 2005 OBJECTIVE: To assess the effectiveness of 600 microg oral misoprostol on postpartum haemorrhage (PPH) and postpartum anaemia in a low income country home birth situation. DESIGN: Double blind randomised controlled trial.
Blum, Jennifer +6 more
core +1 more source
PLoS Neglected Tropical Diseases, 2023 BackgroundThere is a lack of systematic evidence for strategies to control loiasis transmission in highly endemic regions. Here we assessed albendazole and ivermectin based treatment regimens to reduce Loa loa microfilaraemia in Gabon.MethodsEligible ...
Rella Zoleko-Manego +15 more
doaj +1 more source
PLOS Neglected Tropical Diseases, 2023 Moxidectin (MOX) is a milbemycin endectocide recently approved by the U.S. FDA for the treatment of onchocerciasis in persons at least 12 years of age. MOX has been shown to have a good safety profile in recent clinical trials. The efficacy of MOX for the treatment of lymphatic filariasis (LF) and its potential use in mass drug administration protocols
Yashpal S. Chhonker +12 more
openaire +4 more sources
“Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa's Neglected Tropical Diseases Could Benefit the Poor [PDF]
, 2005 Controlling seven tropical infections in Africa would cost just 40 cents per person per year, and would permanently benefit hundreds of millions of ...
Alan Fenwick +14 more
core +4 more sources
Albendazole alone vs. albendazole and diethylcarbamazine combination therapy for trichuriasis [PDF]
Paediatrica Indonesiana, 2013 Background Trichuris trichiura is one of the most commonsoil-transmitted helminths, estimated to infect l billion peopleworldwide. Several studies have compared the efficacies ofalbendazole and diethylcarbamazine, but the efficacy of acombination of these two drugs has been inconclusive.Objective To assess the effectiveness of a single dose ...
Ayodhia Pitaloka Pasaribu +4 more
openaire +2 more sources
Detection of benzimidazole carbamates and amino metabolites in liver by surface plasmon resonance-biosensor [PDF]
, 2011 This research was funded by the Irish Department of Agriculture, Fisheries and Food under the Food Institutional Research Measure as part of the National Development Plan (Project 05/R&D/TN/355)peer-reviewedTwo surface plasmon resonance (SPR) biosensor ...
Brandon, David +5 more
core +1 more source