Results 11 to 20 of about 49,965 (274)

Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: A systematic review, meta-analysis and individual patient data analysis.

PLoS Neglected Tropical Diseases, 2018
BackgroundThe soil-transmitted helminths (STH), Ascaris lumbricoides, Trichuris trichiura and hookworms, infect 1.5 billion people worldwide and cause an estimated burden of 3.3 million disability-adjusted life years (DALYs).
Marta S Palmeirim, Eveline Hürlimann, Stefanie Knopp, Benjamin Speich, Vicente Belizario, Serene A Joseph, Michel Vaillant, Piero Olliaro, Jennifer Keiser   +8 more
doaj   +2 more sources

Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice

Biomolecules, 2020
Currently, Angiostrongylus cantonensis infections are predominantly treated with albendazole. However, the use of albendazole can provoke certain neurological symptoms as a result of the immune response triggered by the dead worms.
Ho Yin Pekkle Lam, Ting-Ruei Liang, Shinn-Jong Jiang, Shih-Yi Peng   +3 more
doaj   +2 more sources

Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity

Molecules, 2020
Albendazole is a benzimidazole derivative with documented antitumor activity and low toxicity to healthy cells. The major disadvantage in terms of clinical use is its low aqueous solubility which limits its bioavailability.
Roxana Racoviceanu, Cristina Trandafirescu, Mirela Voicu, Roxana Ghiulai, Florin Borcan, Cristina Dehelean, Claudia Watz, Zoltán Aigner, Rita Ambrus, Dorina Elena Coricovac, Denisa Cîrcioban, Alexandra Mioc, Camelia Alexandrina Szuhanek, Codruţa Şoica   +13 more
doaj   +2 more sources

Evaluation of the Protoscolicidal Effects of Albendazole and Albendazole Loaded Solid Lipid Nanoparticles

Iranian Journal of Parasitology, 2019
Background: Protoscolex plays an important role in the development of hydatid cyst. Albendazole is one of the most effectual protoscolicidal agents for averting the reappearance of this disease, nonetheless, its low solubility and its low intestinal ...
Shohreh AMINPOUR, Abdollah RAFIEI, Ali JELOWDAR, Maryam KOUCHAK   +3 more
doaj   +2 more sources

Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update

Korean Journal of Parasitology, 2021
The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed.
J. Chai, Bong-Kwang Jung, Sung-Jong Hong
semanticscholar   +1 more source

Different gut microbial communities correlate with efficacy of albendazole-ivermectin against soil-transmitted helminthiases

Nature Communications, 2022
Soil-transmitted helminth infections represent a large burden with over a quarter of the world’s population at risk. Low cure rates are observed with standard of care (albendazole); therefore, a more effective combination therapy (albendazole and ...
P. H. Schneeberger, M. Gueuning, S. Welsche, Eveline Hürlimann, J. Dommann, Cécile Häberli, J. Frey, S. Sayasone, J. Keiser   +8 more
semanticscholar   +1 more source

Efficacy of triple dose albendazole treatment for soil-transmitted helminth infections

PLoS ONE, 2022
In Malaysia, soil-transmitted helminth (STH) infections still persist among indigenous communities. In the past, local studies have focused mostly on epidemiologic aspects of STH infections with a scarcity of information on the efficacy of deworming ...
M. Z. Tee, S. Lee, Y. X. Er, N. Yap, R. Ngui, Alice V. Easton, Vinnie Wei Yin Siow, K. Ng, C. Boey, K. Chua, K. Cadwell, P. Loke, Y. Lim   +12 more
semanticscholar   +1 more source

Evaluation of albendazole efficiency and complications in patients with pulmonary hydatid cyst

Interactive Cardiovascular and Thoracic Surgery, 2021
OBJECTIVES This study investigated the efficacy and complications of albendazole use after surgery in patients with pulmonary hydatid cysts. METHODS One hundred fifty-three consecutive patients who met the study criteria out of 215 patients who received ...
Y. Aydın, A. Ulaş, I. İnce, Asli Kalin, F. Can, B. Gundogdu, Kamber Kaşali̇, B. Kerget, Yasemin Ogul, A. Eroğlu   +9 more
semanticscholar   +1 more source

Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: Results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania

PLoS Neglected Tropical Diseases, 2021
Background Preventive chemotherapy is the cornerstone of soil-transmitted helminth (STH) control. Long-term outcomes and adequate treatment frequency of the recently recommended albendazole-ivermectin have not been studied to date.
Ladina Keller, S. Welsche, Chandni Patel, S. Sayasone, S. Ali, S. Ame, J. Hattendorf, Eveline Hürlimann, J. Keiser   +8 more
semanticscholar   +1 more source

Clinical Efficacy and Safety of Albendazole and Other Benzimidazole Anthelmintics for Rat Lungworm Disease (Neuroangiostrongyliasis): A Systematic Analysis of Clinical Reports and Animal Studies

Clinical Infectious Diseases, 2021
The safety and efficacy of benzimidazole anthelmintics for the treatment of rat lungworm disease (neuroangiostrongyliasis) have been questioned regardless of numerous experimental animal studies and clinical reports.
J. Jacob, Argon Steel, Zhai Lin, Fiona Berger, Katrin Zöeller, S. Jarvi   +5 more
semanticscholar   +1 more source