Results 21 to 30 of about 20,493 (168)

Effect of Sambucus Ebulus Extract and Erythromycin on Albendazole-Induced Histomorphometric Changes in Placenta of Rat

مجله دانشکده پزشکی اصفهان, 2018
Background: There are some reports that albendazole passes placenta and causes disorders in fetus. Besides, there is some evidence that the effect apparently is related to its active metabolite, albendazole sulfoxide.
Mahmood Khaksary-Mahabady, Reza Ranjbar, Hossein Najafzadeh-Varzi, Hasan Morovvati, Elnaz Lak   +4 more
doaj   +1 more source

Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice

Biomolecules, 2020
Currently, Angiostrongylus cantonensis infections are predominantly treated with albendazole. However, the use of albendazole can provoke certain neurological symptoms as a result of the immune response triggered by the dead worms.
Ho Yin Pekkle Lam, Ting-Ruei Liang, Shinn-Jong Jiang, Shih-Yi Peng   +3 more
doaj   +1 more source

Pharmacokinetic Characterization and Comparative Bioavailability of an Innovative Orodispersible Fixed-Dose Combination of Ivermectin and Albendazole: A Single Dose, Open Label, Sequence Randomized, Crossover Clinical Trial in Healthy Volunteers

Frontiers in Pharmacology, 2022
Soil-transmitted helminths are intestinal worm diseases transmitted through the soil. Available treatments are albendazole and/or ivermectin. The co-administration of existing drugs is an appropriate strategy.
Jaime Algorta, Alejandro Krolewiecki, Alejandro Krolewiecki, Filipe Pinto, Silvia Gold, Jose Muñoz   +5 more
doaj   +1 more source

Melatonin in Combination with Albendazole or Albendazole Sulfoxide Produces a Synergistic Cytotoxicity against Malignant Glioma Cells through Autophagy and Apoptosis

Brain Sciences, 2023
Glioblastoma is the most aggressive and lethal brain tumor in adults, presenting diffuse brain infiltration, necrosis, and drug resistance. Although new drugs have been approved for recurrent patients, the median survival rate is two years; therefore ...
Miguel Hernández-Cerón, Víctor Chavarria, Camilo Ríos, Benjamin Pineda, Francisca Palomares-Alonso, Irma Susana Rojas-Tomé, Helgi Jung-Cook   +6 more
doaj   +1 more source

Drug Induced Liver Injury by Prophylactic Administration of Albendazole

The Korean Journal of Gastroenterology, 2019
Albendazole is used as a typical antiparasitic agent worldwide. The side effects of albendazole may include nausea, vomiting, abdominal pain, dizziness, headache, alopecia, and increased liver enzymes. Mild elevation of the liver enzyme has been reported
Sang Yi Moon, Yang Hyun Baek, Sung Wook Lee   +2 more
doaj   +1 more source

Exposure of Heligmosomoides polygyrus and Trichuris muris to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate in vitro and in vivo to elucidate the pathway of drug entry into these gastrointestinal nematodes

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for
Noemi Cowan, Charles Meier, Anna Neodo, Jennifer Keiser   +3 more
doaj   +1 more source

Isolated splenic cystic echinococcosis and albendazole hepatotoxicity

IDCases, 2022
Isolated splenic cystic echinococcosis is a rare condition. In Greece the number of cases has declined substantially in the last 20 years. The spleen is the second most common extrahepatic site of cystic echinococcosis.
Nikolaos Moussas, Sotirios Adamidis, Nikolaos Adamidis, Charalabos Stratopoulos, Panagiotis Gargalianos-Kakolyris   +4 more
doaj   +1 more source

Comparison of albendazole cytotoxicity in terms of metabolite formation in four model systems

Journal of Veterinary Research, 2017
Introduction: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone.
Radko Lidia, Minta Maria, Jedziniak Piotr, Stypuła-Trębas Sylwia   +3 more
doaj   +1 more source

Two or Three Consecutive Days Albendazole Treatment Has Better Efficacy than Single-Dose Albendazole Treatment for Trichuriasis

Indonesian Biomedical Journal, 2020
BACKGROUND: Soil-transmitted helminth (STH) infection is endemic in Indonesia. Singledose albendazole is routinely used to control STH infections. Some studies found that repeated-dose of albendazole showed better efficacy. There is no study in Indonesia
Dina Evalina Gultom, Muhammad Ali, Ayodhia Pitaloka Pasaribu, Syahril Pasaribu   +3 more
doaj   +1 more source

Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection: a randomized controlled trial. [PDF]

PLoS Neglected Tropical Diseases, 2012
The currently used anthelmintic drugs, in single oral application, have low efficacy against Trichuris trichiura infection, and hence novel anthelmintic drugs are needed. Nitazoxanide has been suggested as potential drug candidate.The efficacy and safety
Benjamin Speich, Shaali M Ame, Said M Ali, Rainer Alles, Jan Hattendorf, Jürg Utzinger, Marco Albonico, Jennifer Keiser   +7 more
doaj   +1 more source