Hydroxyapatite Binding Peptide Lipid Nanoparticles for Biomimetic mRNA Delivery to Bone
Targeted delivery of therapeutic mRNA to peripheral tissues, including bone, is currently challenging. In the current work, a hydroxyapatite binding peptide (HABP) is conjugated to mRNA lipid nanoparticles (LNPs). HABP‐LNPs delivered systemically are demonstrated to reduce transfection in the liver and improve transfection in the femurs of mice ...
Joshua A. Choe+6 more
wiley +1 more source
Association Between Neutrophil Percentage-to-Albumin Ratio and Depression in Middle-Aged and Elderly Adults: A National Study. [PDF]
Zhao L, Li C, Lv H, Zeng C, Peng Y.
europepmc +1 more source
A Commentary on albumin in acidosis
openaire +3 more sources
Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang+7 more
wiley +1 more source
Preoperative pan-immuno-inflammatory values and albumin-to-globulin ratio predict the prognosis of stage I-III colorectal cancer. [PDF]
Li K+8 more
europepmc +1 more source
Proposed Novel Heart Failure Biomarkers and Their Association with Length of Hospital Stay and Mortality: A Retrospective Observational Pilot Study. [PDF]
Cristescu L+4 more
europepmc +1 more source
Association between the lactate dehydrogenase-to-albumin ratio and 28-day mortality in septic patients with malignancies: analysis of the MIMIC-IV database. [PDF]
Shen Y+6 more
europepmc +1 more source
Development of an Online Nomogram for Predicting Postoperative Hypoalbuminemia in Older Adults Following Femoral Neck Fractures. [PDF]
Gong H, Miao H, Hong W, Yu W, Sun Y.
europepmc +1 more source
The impact of the lactate-to-albumin ratio on long-term mortality risk in patients with severe heart failure and type 2 diabetes. [PDF]
Dong Y+8 more
europepmc +1 more source
The Prognostic Value of Platelet-Albumin-Bilirubin Score in Patients Undergoing Transcatheter Aortic Valve Replacement. [PDF]
Khan FU+4 more
europepmc +1 more source