Results 21 to 30 of about 907,553 (313)

THE SIGNIFICANCE OF ALBUMIN AND OF ALBUMIN WITH CASTS IN THE URINE* [PDF]

American Journal of Epidemiology, 1921
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openaire   +2 more sources

A Comprehensive Immunocapture-LC-MS/MS Bioanalytical Approach in Support of a Biotherapeutic Ocular PK Study

Pharmaceuticals
BI-X, a therapeutic protein under development for the treatment of human ocular disease via intravitreal administration, binds to its therapeutic targets and endogenous albumin in the vitreous humor.
Lin-Zhi Chen, David Roos, Elsy Philip, Emily G. Werth, Stephanie Kostuk, Hongbin Yu, Holger Fuchs   +6 more
doaj   +1 more source

GP60 and SPARC as albumin receptors: key targeted sites for the delivery of antitumor drugs

Frontiers in Pharmacology
Albumin is derived from human or animal blood, and its ability to bind to a large number of endogenous or exogenous biomolecules makes it an ideal drug carrier. As a result, albumin-based drug delivery systems are increasingly being studied.
Qingzhi Ji, Huimin Zhu, Yuting Qin, Ruiya Zhang, Lei Wang, Erhao Zhang, Xiaorong Zhou, Run Meng   +7 more
doaj   +1 more source

Albumin cayemite: A Negro plasma albumin variant [PDF]

Human Genetics, 1969
An inherited variant of human serum albumin has been found in a Negro family from Haiti. The variant is electrophoretically distinguishable from ten different previously reported types of albumin variants.
Basu, A., Weitkamp, Lowell R., Gall, John C., Brown, W.   +3 more
openaire   +4 more sources

The Prognostic Value of New Index (LANR) Composed of Pre-operative Lymphocytes, Albumin, and Neutrophils in Patients With Resectable Colorectal Cancer

Frontiers in Oncology, 2021
Background: Inflammatory factors and nutritional status are critical to the prognosis of colorectal cancer patients. This study aimed to investigate the prognostic value of the combination of preoperative lymphocytes, albumin, and neutrophils (LANR) in ...
Xinjun Liang, Xinjun Liang, Xinjun Liang, Shuang Yao, Shuang Yao, Shuang Yao, Ping Lu, Ping Lu, Ping Lu, Yifei Ma, Yifei Ma, Yifei Ma, Hongli Xu, Hongli Xu, Hongli Xu, Zhucheng Yin, Zhucheng Yin, Zhucheng Yin, Junjie Hu, Junjie Hu, Junjie Hu, Yanyan Liu, Shaozhong Wei, Shaozhong Wei, Shaozhong Wei   +24 more
doaj   +1 more source

Physicochemical and Functional Properties of 2S, 7S, and 11S Enriched Hemp Seed Protein Fractions

Molecules, 2022
The hemp seed contains protein fractions that could serve as useful ingredients for food product development. However, utilization of hemp seed protein fractions in the food industry can only be successful if there is sufficient information on their ...
Comfort F. Ajibola, Rotimi E. Aluko
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy

Pharmaceutics, 2021
Prodrugs are bioreversible medications that should undergo an enzymatic or chemical transformation in the tumor microenvironment to release active drugs, which improve cancer selectivity to reduce toxicities of anticancer drugs.
Hanhee Cho, Man Kyu Shim, Suah Yang, Sukyung Song, Yujeong Moon, Jinseong Kim, Youngro Byun, Cheol-Hee Ahn, Kwangmeyung Kim   +8 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

How Different Albumin-Binders Drive Probe Distribution of Fluorescent RGD Mimetics

Frontiers in Chemistry, 2021
The biodistribution of medical imaging probes depends on the chemical nature of the probe and the preferred metabolization and excretion routes. Especially targeted probes, which have to reach a certain (sub)cellular destination, have to be guided to the
Carsten Höltke, Wael Alsibai, Martin Grewer, Miriam Stölting, Christiane Geyer, Michel Eisenblätter, Michel Eisenblätter, Moritz Wildgruber, Moritz Wildgruber, Anne Helfen   +9 more
doaj   +1 more source