Results 131 to 140 of about 92,432 (365)

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

Albumin in cell culture media – An examination of quality and function [PDF]

open access: yes, 2017
The inclusion of human serum albumin into serum free cell culture media (SFM) has been shown to be extremely beneficial in expanding multiple therapeutically relevant cell types ex vivo.
Alfano, Randall W.
core   +1 more source

Albumin and multiple sclerosis [PDF]

open access: yesBMC Neurology, 2016
Leakage of the blood-brain barrier (BBB) is a common pathological feature in multiple sclerosis (MS). Following a breach of the BBB, albumin, the most abundant protein in plasma, gains access to CNS tissue where it is exposed to an inflammatory milieu and tissue damage, e.g., demyelination.
openaire   +4 more sources

Interaction of cyclodextrins with human and bovine serum albumins: a combined spectroscopic and computational investigation [PDF]

open access: yes, 2014
Interaction of cyclodextrins (CDs) with the two most abundant proteins, namely human serum albumin (HSA) and bovine serum albumin (BSA), has been investigated using steady-state and time-resolved fluorometric techniques, circular dichroism measurements ...
Chattopadhyay, Nitin   +2 more
core   +1 more source

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces [PDF]

open access: yeseJournal of Oral Maxillofacial Research, 2010
Objectives: To observe the early adsorption of extracellular matrix and blood plasma proteins to magnesium-incorporated titanium oxide surfaces, which has shown superior bone response in animal models.Material and Methods: Commercially pure titanium ...
Ryo Jimbo   +4 more
doaj  

ANALYSIS OF PROTEIN ISOLATE FROM QUINOA (CHENOPODIUM QUINOA WILLD) [PDF]

open access: yes, 2016
Objective: The aim of this study was to obtain protein isolate from quinoa using alkaline pH at different pHs of precipitation and to analyze proteinisolate with electrophoresis.Methods: Quinoa protein isolates were obtained using isoelectric ...
A, Toapanta   +3 more
core   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib   +16 more
wiley   +1 more source

Evaluation of the Laboratorial Profile of Elderlies with Proximal Femur Fracture by Low Energy Mechanism

open access: yesRevista Brasileira de Ortopedia
Objective This study aims to evaluate the laboratory results profile of elderly patients with proximal femoral fractures and to verify the relationship between these data, fracture outcome and death. Methods Cross-sectional study of patients admitted to
Marcelo Baggio   +2 more
doaj   +1 more source

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