Results 11 to 20 of about 17,343 (263)

Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study

BMJ Open Respiratory Research, 2021
Introduction Uncontrolled asthma is associated with substantial morbidity. While fast-acting bronchodilators provide quick relief from asthma symptoms, their use as rescue fails to address the underlying inflammation.
Alberto Papi, Bradley E Chipps, Frank C Albers, Laurence Reilly, Eva Johnsson, Christy Cappelletti   +5 more
doaj   +2 more sources

Historical cohort study examining comparative effectiveness of albuterol inhalers with and without integrated dose counter for patients with asthma or chronic obstructive pulmonary disease

Journal of Asthma and Allergy, 2016
David B Price,1,2 Anna Rigazio,2 Mary Buatti Small,3 Thomas J Ferro,3 1Academic Primary Care, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK; 2Research in Real-Life Ltd, Cambridge, UK; 3Teva Pharmaceuticals, Frazer, PA, USA ...
Price DB, Rigazio A, Buatti Small M, Ferro TJ   +3 more
doaj   +2 more sources

Albuterol in the treatment of acute respiratory distress syndrome: A meta-analysis of randomized controlled trials [PDF]

World Journal of Emergency Medicine, 2015
BACKGROUND This meta-analysis of randomized controlled trials aimed to systematically evaluate the value of albuterol in the treatment of patients with acute respiratory distress syndrome (ARDS).
Ruo Wu, Shi-yun Lin, Huimin Zhao
openalex   +2 more sources

Albuterol-Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma.

New England Journal of Medicine, 2022
BACKGROUND As asthma symptoms worsen, patients typically rely on short-acting β2-agonist (SABA) rescue therapy, but SABAs do not address worsening inflammation, which leaves patients at risk for severe asthma exacerbations.
A. Papi, B. Chipps, R. Beasley, R. Panettieri, E. Israel, M. Cooper, L. Dunsire, A. Jeynes-Ellis, E. Johnsson, R. Rees, C. Cappelletti, F. Albers   +11 more
semanticscholar   +1 more source

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series

Molecular Medicine, 2020
Mechanically ventilated patients with COVID-19 have a mortality of 24–53%, in part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil extracellular traps (NETs) contribute to the viscosity of mucopurulent secretions ...
Andrew Weber, A. Chau, M. Egeblad, B. Barnes, T. Janowitz   +4 more
semanticscholar   +2 more sources

For which infants with viral bronchiolitis could it be deemed appropriate to use albuterol, at least on a therapeutic trial basis?

Allergologia et Immunopathologia, 2021
Although there is increasing evidence showing that infants with viral bronchiolitis exhibit a high degree of heterogeneity, a core uncertainty shared by many clinicians is with regard to understanding which patients are most likely to benefit from ...
C. Rodríguez‐Martínez, G. Nino, J. Castro-Rodriguez, R. Acuña-Cordero, Mónica P. Sossa-Briceño, F. Midulla   +5 more
semanticscholar   +1 more source

Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance While intravenous magnesium decreases hospitalizations in refractory pediatric acute asthma, it is variably used because of invasiveness and safety concerns.
S. Schuh, J. Sweeney, Maggie Rumantir, A. Coates, A. Willan, D. Stephens, E. Atenafu, Y. Finkelstein, G. Thompson, R. Zemek, A. Plint, J. Gravel, F. Ducharme, David W Johnson, K. Black, Sarah Curtis, Darcy L Beer, T. Klassen, Darcy Nicksy, S. Freedman   +19 more
semanticscholar   +1 more source

Nebulized heparin and salbutamol versus salbutamol alone in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation: a double-blind randomized controlled trial [PDF]

Korean Journal of Anesthesiology, 2020
Background Nebulized heparin has been effectively used in the management of many pulmonary diseases. However, its effect on mechanically ventilated patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) has never been studied ...
Tarek Mohamed Ashoor, Ahmad Mahmoud Hasseb, Ibrahim Mamdouh Esmat   +2 more
doaj   +1 more source

A meta‐analysis of the influence of ADRB2 genetic polymorphisms on albuterol (salbutamol) therapy in patients with asthma

British Journal of Clinical Pharmacology, 2020
The associations of 2 nonsynonymous single nucleotide polymorphisms (Arg16Gly and Gln27Glu) in the adrenoceptor β2 (ADRB2) gene with response after albuterol use are conflicting.
K. Hikino, Shinobu Kobayashi, E. Ota, T. Mushiroda, K. Urayama, Tohru Kobayashi   +5 more
semanticscholar   +1 more source

(R)-albuterol decreases immune responses: role of activated T cells

Respiratory Research, 2008
Racemic albuterol is an equimolar mixture of two isomers, (R) and (S). Whether (R) and (S) isomers and the combination of both exert different effects in immune activation is not well defined. We analyzed the effects of (R+S)-albuterol, (R)-albuterol and
Lu Xin, He Hong, Jen Kai, Gordon Erin L, Ferrada Marcela A, Barone Leesa M, Amirifeli Sepideh, Perkins David L, Finn Patricia W   +8 more
doaj   +1 more source