Results 231 to 240 of about 91,956 (289)

Potential Role of Liver Transplantation for Child–Pugh Class A Hepatocellular Carcinoma: Prognosis and Medical Expenditure in Japan—A Retrospective Single‐Center Study

Hepatology Research, EarlyView.
Among patients with CP‐A HCC initially within the Japan criteria, some lose oncological eligibility for LT before hepatic decompensation. Further studies are needed to identify baseline factors associated with poor outcomes and to evaluate their relevance to future LT candidacy.
Akihiro Seki, Tomoyoshi Chiba, Shintaro Yagi, Rika Horii, Noboru Takata, Hiroki Nomura, Masaki Miyazawa, Tomoyuki Hayashi, Takeshi Terashima, Shinichi Nakanuma, Mitsuyoshi Okazaki, Satoshi Takada, Tatsuya Yamashita, Masao Honda, Hajime Takatori, Tetsuro Shimakami, Taro Yamashita   +16 more
wiley   +1 more source

Iron Overload: Pathophysiology, Diagnosis and Monitoring

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Iron overload is associated with significant health risks, underscoring the importance of understanding its pathophysiology as well as establishing accurate diagnostic and monitoring methods. Chronic iron overload is associated with either genetic disorders characterized by excessive iron accumulation (hereditary hemochromatosis), or is ...
Elena Chatzikalil, Polyxeni Delaporta, Konstantinos Bistas, Antonis Kattamis   +3 more
wiley   +1 more source

A prospective study of 12‐month survival of patients with cirrhosis admitted to intensive care

Internal Medicine Journal, EarlyView.
Abstract Background The assessment on whether to escalate care in patients with cirrhosis to the intensive care unit (ICU) is complex, with little data on long‐term outcomes. The primary aim of this study was to prospectively examine the ability of liver‐specific and ICU prognostic scores to predict 12‐month survival among patients with cirrhosis in ...
Minnie Au, Xian J Mah, Sern W Yeoh, Anh D Pham, Ashley Bloom, Nina Parthasarathy, Stephen D Bloom, Rohit Sawhney, Peter Oziemski, Amanda J Nicoll   +9 more
wiley   +1 more source

Healthcare costs of managing MAFLD are mostly driven by hospitalisation and advanced fibrosis: cost‐analysis from a tertiary‐care, multi‐disciplinary MAFLD clinic

Internal Medicine Journal, EarlyView.
Abstract Background and Aims Patients with metabolic (dysfunction)‐associated fatty liver disease (MAFLD) are frequently multimorbid, putting upward pressure on healthcare costs compared to other liver diseases. As Australian data are limited on expenditures in managing MAFLD, we evaluated hospital‐related costs and predictors of costs in patients ...
Natalie Ngu, Karl Vaz, Tobie Abrahams, Carmela Cosentino, John Lubel, Ammar Majeed, Stuart K Roberts, William Kemp   +7 more
wiley   +1 more source

The role and uptake of drug and alcohol services in patients with alcohol‐associated acute pancreatitis at a large multisite health service

Internal Medicine Journal, EarlyView.
Abstract Background Alcohol consumption remains an independent risk factor for recurrent presentations of alcohol‐associated acute pancreatitis (AAP). Although there are recognised guidelines for alcohol use disorder (AUD), there are no recommendations on targeting alcohol cessation to reduce recurrence of AAP in guidelines for acute pancreatitis ...
Cindy Ho, Hardesh Dhillon, Alexander Mitropoulos, Eliza Flanagan, Timothy Phan, Joshua Haron Abasszade, Jeremy Tse, Bowen Xia, Kyle Williams, Faris Gondal, Sally Jane Bell, David Jacka, Simon Hew   +12 more
wiley   +1 more source

Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL

Immunology, EarlyView.
In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten, Amy Lumley, Alex L. Wilkinson, Ayla O’Keeffe, Kelvin Yin, Niranjan Shirgaonkar, Ran Gao, Ramanuj DasGupta, Matthew Hoare, Shishir Shetty   +9 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Global analysis of incidence trends and projections of liver cirrhosis among women of childbearing age: An observational study based on the Global Burden of Disease data. [PDF]

Medicine (Baltimore)
Cheng P, Sun Y, Qiang Y, Wu J, Duan B, Li G.   +5 more
europepmc   +1 more source

Premature closure underlies bias in medical diagnosis in students: A randomised controlled experiment

Medical Education, EarlyView.
Abstract Objective The purpose of the study reported in this article was to shed light on the cognitive mechanism mediating between biasing information and diagnostic error. The literature suggests at least two different hypotheses: premature closure leading biased participants to spend less time on diagnosis or increased competition between diagnostic
Awad Al Essa, Henk G. Schmidt, Silvia Mamede, Karla Knežević, Laura Zwaan, Mohi Magzoub   +5 more
wiley   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source