Results 171 to 180 of about 282,239 (282)

Multiplexed targeted mRNA profiling of alcohol-related liver disease reveals stage-specific dysregulation of signaling pathways. [PDF]

Mol Biol Rep
Rasic D, Thiele M, Andersen P, Krag A, Detlefsen S.   +4 more
europepmc   +1 more source

Alcoholic liver disease in Nepal: identifying homemade alcohol as a culprit

, 2015
Bickram Pradhan,1 Antoine Hadengue,2 François Chappuis,3 Shatdal Chaudhary,1 Dharanidhar Baral,4 Pascal Gache,5 Prahlad Karki,6 Suman Rijal6 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, B P Koirala Institute of ...
Gache P, Pradhan B, Hadengue A, Chaudhary S, Baral D, Karki P, Chappuis F, Rijal S   +7 more
core  

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source

Non-invasive tests for MetALD and alcohol-related liver disease. [PDF]

JHEP Rep
Johansen S, Thiele M, Krag A.
europepmc   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism. [PDF]

JHEP Rep
Keller MI, de Zawadzki A, Thiele M, Suvitaival T, Sulek K, Kuhn M, Schudoma C, Podlesny D, Nishijima S, Fullam A, Kim CY, Niu L, Wretlind A, Hansen JK, Israelsen M, Johansen S, Akanni W, Hazenbrink D, Juel HB, Mann M, Hansen T, Krag A, Bork P, Legido-Quigley C, GALAXY & MicrobLiver consortia.   +24 more
europepmc   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Medications for Alcohol Use Disorder Among Patients With Severe Alcohol-Related Liver Disease. [PDF]

JAMA Netw Open
Sundaresh R, Singh J, Meza J, Saab S, Shetty A.   +4 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Prognostic associations of vitamin D deficiency with disease severity, survival, and complications in alcohol-related liver disease. [PDF]

Front Med (Lausanne)
He Q, Duan F, Mao C, Cheng J, Wang Y, Zeng Y, Yang S.   +6 more
europepmc   +1 more source