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Epigenetic modification in alcohol‐related liver diseases
Medicinal Research Reviews, 2022AbstractAlcohol‐related liver disease (ARLD) refers to a spectrum of hepatic damage triggered by excessive alcohol intake, resulting in inflamed and swollen livers, ultimately, liver cirrhosis. Alcoholic liver disease (ALD) is a similar term denoting liver disorders encompassing steatosis, cirrhosis, and hepatocellular carcinoma.
Amir Ajoolabady +3 more
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Prognostic models in alcohol-related liver disease and alcohol-related hepatitis
Best Practice & Research Clinical Gastroenterology, 2023Alcohol-associated liver disease (ALD) and alcohol-associated hepatitis (AH) are dynamic disorders whose prognosis can be challenging to determine. A number of prognostic models have been developed to determine likelihood of death, when to refer for liver transplant (LT) and the role for glucocorticoids.
Jessica Ann Musto, Michael Ronan Lucey
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Nutrition in Alcohol-Related Liver Disease
Current Hepatology Reports, 2022Purpose of Review Alcohol use represents one of the five major causes of morbimortality globally, and alcohol-related liver disease (ALD) is the most common cause of cirrhosis worldwide. Malnutrition is one of the most frequent complications in ALD and is associated with decreased survival.
María Ayala-Valverde +5 more
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The Genetics of Alcohol-Related Liver Disease
2023Significant advances into the genetics of alcohol-related liver disease (ALD) have been made in the last two decades. Most notably, this includes the discovery of ten common genetic variants associated either with alcohol-related cirrhosis and/or hepatocellular carcinoma. These novel associations provide insight into the pathophysiology of ALD and have
Innes, Hamish, Stickel, Felix
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Decompensated alcohol related liver disease: acute management
BMJ, 2016#### What you need to know Alcohol related liver disease (ARLD) and liver cirrhosis are complications of long term excessive alcohol use and occur in 10-20% of chronic, heavy drinkers.1 2 Complications, including hepatic decompensation, variceal bleeding, and hepatocellular carcinoma, reduce life expectancy.1 3 Since 1970, there has been a 400 ...
McPherson S, Lucey MR, Moriarty KJ
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Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2022
Sheeba Khan, Owen Cain, Neil Rajoriya
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Sheeba Khan, Owen Cain, Neil Rajoriya
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The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
Nature Reviews Gastroenterology and Hepatology, 2023Luis Antonio Díaz +2 more
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The gut–liver axis and gut microbiota in health and liver disease
Nature Reviews Microbiology, 2023Cynthia Li-Shin Hsu
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Noninvasive proteomic biomarkers for alcohol-related liver disease
Nature Medicine, 2022Lili Niu +2 more
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