Results 21 to 30 of about 1,516,378 (315)

Impulsive Lifestyle Counselling versus treatment as usual to reduce offending in people with co-occurring antisocial personality disorder and substance use disorder: a post hoc analysis

open access: yesBMC Psychiatry, 2022
Objectives To assess the impact of a short psychoeducation intervention for antisocial personality disorder on offending after randomization to treatment. Design Multicentre, superiority, non-blinded randomized controlled trial.
Morten Hesse   +2 more
doaj   +1 more source

A molecular equation of state for alcohols which includes steric hindrance in hydrogen bonding [PDF]

open access: yesThe Journal of Chemical Physics 149, 044505 (2018), 2018
In this paper we develop the first equation of state for alcohol containing mixtures which includes the effect of steric hindrance between the two electron lone pair hydrogen bond acceptor sites on the alcohol's hydroxyl oxygen. The theory is derived for multi-component mixtures within Wertheim's multi-density statistical mechanics in a second order ...
arxiv   +1 more source

4191 The Role of Suggestibility and Trait Anxiety in Young Adult Alcohol Use

open access: yesJournal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: The purpose of this study was to investigate how suggestibility and social susceptibility relate to alcohol use in young adult non-dependent alcohol users, and the role of trait anxiety in this relationship. We hypothesized that greater
Alexandra Cowand   +6 more
doaj   +1 more source

Is there any linkage between interstellar aldehyde and alcohol? [PDF]

open access: yes, 2021
It is speculated that there might be some linkage between interstellar aldehydes and their corresponding alcohols. Here, an observational study and astrochemical modeling are coupled together to illustrate the connection between them. The ALMA Cycle 4 data of a hot molecular core, G10.47+0.03 is utilized for this study. Various aldehydes (acetaldehyde,
arxiv   +1 more source

Alcohol. [PDF]

open access: yesBMJ, 1982
Abstract There is evidence for a dose-response relationship between alcohol consumption and risk of liver cirrhosis, cancers of the oropharynx, larynx, oesophagus, rectum (beer only), liver, and female breast, and violent death, but the relationship between alcohol consumption and cardiovascular disease is more complex.
openaire   +2 more sources

Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans

open access: yesCommunications Biology, 2023
Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in ...
Dardo Tomasi   +15 more
doaj   +1 more source

cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease

open access: yesBiomolecules, 2020
The importance of cyclic adenosine monophosphate (cAMP) in cellular responses to extracellular signals is well established. Many years after discovery, our understanding of the intricacy of cAMP signaling has improved dramatically.
Mohamed Elnagdy   +3 more
doaj   +1 more source

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain

open access: yesScientific Reports, 2022
The continuous rise in opioid overdoses in the United States is predominantly driven by very potent synthetic opioids, mostly fentanyl and its derivatives (fentanyls).
Yeona Kang   +14 more
doaj   +1 more source

Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques

open access: yesBiomolecules, 2022
Effective antiretroviral therapy (ART) has transitioned HIV to a chronic disease, with more than 50% of people living with HIV (PLWH) being over the age of 50.
Patrick M. McTernan   +5 more
doaj   +1 more source

Cholesterol as a modulator of cannabinoid receptor CB2 signaling

open access: yesScientific Reports, 2021
Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB2, we demonstrate that cholesterol increases basal ...
Alexei Yeliseev   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy