Acute alcohol administration dampens central extended amygdala reactivity. [PDF]
, 2018 Alcohol use is common, imposes a staggering burden on public health, and often resists treatment. The central extended amygdala (EAc)-including the bed nucleus of the stria terminalis (BST) and the central nucleus of the amygdala (Ce)-plays a key role in
Bradford, Daniel E +6 more
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BMC Psychiatry, 2022 Objectives To assess the impact of a short psychoeducation intervention for antisocial personality disorder on offending after randomization to treatment. Design Multicentre, superiority, non-blinded randomized controlled trial.
Morten Hesse +2 more
doaj +1 more source
Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]
, 2017 Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy +16 more
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4191 The Role of Suggestibility and Trait Anxiety in Young Adult Alcohol Use
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: The purpose of this study was to investigate how suggestibility and social susceptibility relate to alcohol use in young adult non-dependent alcohol users, and the role of trait anxiety in this relationship. We hypothesized that greater
Alexandra Cowand +6 more
doaj +1 more source
Relationship between tonic and phasic craving for alcohol. [PDF]
, 2018 BackgroundMultiple measures are utilized to assess alcohol craving, often interchangeably. Little is known about the relationship between tonic and phasic craving.
Hartwell, Emily E, Ray, Lara A
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cAMP Signaling in Pathobiology of Alcohol Associated Liver Disease
Biomolecules, 2020 The importance of cyclic adenosine monophosphate (cAMP) in cellular responses to extracellular signals is well established. Many years after discovery, our understanding of the intricacy of cAMP signaling has improved dramatically.
Mohamed Elnagdy +3 more
doaj +1 more source
Cholesterol as a modulator of cannabinoid receptor CB2 signaling
Scientific Reports, 2021 Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB2, we demonstrate that cholesterol increases basal ...
Alexei Yeliseev +7 more
doaj +1 more source
The Serotonin Transporter Polymorphism (5-HTTLPR) and Alcohol Problems in Heavy Drinkers: Moderation by Depressive Symptoms. [PDF]
, 2011 Heavy alcohol use in young adults has been prospectively associated with a host of psychosocial and alcohol-related problems. Recent studies have supported the interaction between serotonin transporter polymorphism and adverse environmental factors, as a
Ray, Lara A, Tartter, Molly A
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Do patients who die from an alcohol-related condition ‘drift’ into areas of greater deprivation? Alcohol-related mortality and health selection theory in Scotland [PDF]
, 2017 Background: Health selection has been proposed to explain the patterning of alcohol-related mortality by area deprivation. This study investigated whether persons who die from alcohol-related conditions are more likely to experience social drift than ...
Gordon, Ruth +5 more
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Journal of Lipid Research, 1977 Short- and long-term effects of ethanol on HMG-CoA reductase (EC 1.1.1.34) and cholesterol 7α-hydroxylase activities in rat liver have been investigated.
M R Lakshmanan, R L Veech
doaj +1 more source