Results 51 to 60 of about 4,496,597 (381)

Effectiveness of brief alcohol interventions in primary care populations.

open access: yesCochrane Database of Systematic Reviews, 2018
BACKGROUND Excessive drinking is a significant cause of mortality, morbidity and social problems in many countries. Brief interventions aim to reduce alcohol consumption and related harm in hazardous and harmful drinkers who are not actively seeking help
E. Kaner   +8 more
semanticscholar   +1 more source

Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries (preprint)

open access: yes, 2021
Aims: The aim of this project was to investigate changes in alcohol consumption during the first months of the pandemic in Europe as well as its associations with income and experiences of distress related to the COVID-19 pandemic.
C. Kilian   +14 more
semanticscholar   +1 more source

Chronological relationship between antisocial personality disorder and alcohol dependence [PDF]

open access: yes, 2002
Personality disorders, and particularly antisocial personality disorder (ASPD), frequently co-occur with alcohol dependence. ASPD is considered to be an important cofactor in the pathogenesis and clinical course of alcohol dependence.
Bahlmann, Miriam   +2 more
core   +1 more source

The relationship between different dimensions of alcohol use and the burden of disease—an update

open access: yesAddiction, 2017
Background and aims Alcohol use is a major contributor to injuries, mortality and the burden of disease. This review updates knowledge on risk relations between dimensions of alcohol use and health outcomes to be used in global and national Comparative ...
J. Rehm   +11 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Collectivity of Drinking Behavior Among Adolescents: An Analysis of the Norwegian ESPAD Data 1995-2011

open access: yesNordic Studies on Alcohol and Drugs, 2014
AIMS – The aim of the current study was to test empirically two predictions from Skog’s theory of collectivity of drinking behavior, using time series data from Norwegian adolescents.
Brunborg Geir Scott   +2 more
doaj   +1 more source

Adolescent Initiation and Maintenance: An Analysis of the Roles of Self-Efficacy, Sensation Seeking, Parents, and Peers [PDF]

open access: yes, 2013
Alcohol use among adolescents is a public health concern. Research of the predictors of adolescent alcohol initiation and use are necessary to better combat the negative impacts associated with alcohol use by youth.
Bullock, Benjamin
core   +1 more source

ALDH2*2 and peer drinking in East Asian college students [PDF]

open access: yes, 2017
Background: The ALDH2*2 allele (A-allele) at rs671 is more commonly carried by Asians and is associated with alcohol-related flushing, a strong adverse reaction to alcohol that is protective against drinking.
Chartier, Karen G.   +5 more
core   +2 more sources

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance Alcohol consumption is associated with 88 000 US deaths annually. Although routine screening for heavy alcohol use can identify patients with alcohol use disorder (AUD) and has been recommended, only 1 in 6 US adults report ever having been ...
H. Kranzler, M. Soyka
semanticscholar   +1 more source

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