Results 51 to 60 of about 4,568,665 (381)

ALCOHOL AND ALCOHOLIC INTOXICATION.* [PDF]

open access: yesBritish Journal of Inebriety, 1920
n ...
openaire   +3 more sources

Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats

open access: yesBiology of Sex Differences, 2019
Background Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to conditioned stimuli compared to males, potentially indicating heightened addiction ...
Sierra J. Stringfield   +3 more
doaj   +1 more source

Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration under Similar Systemic Exposures [PDF]

open access: yes, 2019
Objective To test whether an individual's subjective responses to alcohol are similar when the breath alcohol concentration (BrAC) trajectory resulting from oral administration is matched by intravenous administration.
Boes, Julian   +6 more
core   +1 more source

Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans

open access: yesCommunications Biology, 2023
Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in ...
Dardo Tomasi   +15 more
doaj   +1 more source

Trends in Alcohol Services Utilization from 1991–1992 to 2001–2002: Ethnic Group Differences in the U.S. Population [PDF]

open access: yes, 2011
Background:  During the early 1990s in the United States, changes to the provision and financing of alcohol treatment services included reductions in inpatient treatment services and in private sector spending for treatment.
Caetano, Raul, Chartier, Karen G.
core   +2 more sources

Alcohol consumption during the COVID-19 pandemic in Europe: a large-scale cross-sectional study in 21 countries (preprint)

open access: yes, 2021
Aims: The aim of this project was to investigate changes in alcohol consumption during the first months of the pandemic in Europe as well as its associations with income and experiences of distress related to the COVID-19 pandemic.
C. Kilian   +14 more
semanticscholar   +1 more source

Naloxone’s dose-dependent displacement of [11C]carfentanil and duration of receptor occupancy in the rat brain

open access: yesScientific Reports, 2022
The continuous rise in opioid overdoses in the United States is predominantly driven by very potent synthetic opioids, mostly fentanyl and its derivatives (fentanyls).
Yeona Kang   +14 more
doaj   +1 more source

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

open access: yesNature Communications, 2019
Alcohol consumption level and alcohol use disorder (AUD) diagnosis are moderately heritable traits. We conduct genome-wide association studies of these traits using longitudinal Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) scores and ...
H. Kranzler   +19 more
semanticscholar   +1 more source

Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders

open access: yesFrontiers in Psychiatry, 2019
Opioid use in the United States has steadily risen since the 1990s, along with staggering increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid abuse, it is paramount to understand the genetic risk factors and
Jamie A. Burns   +8 more
doaj   +1 more source

Evidence Based Treatment for Excessive Alcohol Consumption and Concurrent Hypertension [PDF]

open access: yes, 2020
Purpose. Excessive alcohol consumption is a preventable risk factor for hypertension, heart disease, and stroke. Though alcohol-related deaths number 88,000 annually in the U.S., alcohol use has the lowest treatment rate of behavioral health disorders at
Ward, Kimberly Ann
core   +1 more source

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