Results 61 to 70 of about 4,496,597 (381)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Cannabis use frequency, route of administration, and co-use with alcohol among older adults in Washington state

Journal of Cannabis Research, 2021
Background The US national surveys and data from legal adult use cannabis states show increases in the prevalence of cannabis use among older adults, though little is known about their manner of cannabis consumption.
Meenakshi S. Subbaraman, William C. Kerr
doaj   +1 more source

Alcohol Use In Mexican-Americans By Nativity: The Role Of Ethnic Identity, Acculturation, And Acculturative Stress [PDF]

, 2013
The present study examined alcohol use disorder symptoms among Mexican-Americans. Participants consisted of a community-based sample of 237 Mexican-American adults living in the Midwest United States. The role of nativity status and cultural variables in
Vallejo, Leticia G.
core   +1 more source

Effects of Policies Designed to Keep Firearms from High-Risk Individuals [PDF]

, 2015
This article summarizes and critiques available evidence from studies published between 1999 and August 2014 on the effects of policies designed to keep firearms from high-risk individuals in the United States. Some prohibitions for high-risk individuals
Am. for Gun Saf. Found, Blumstein A, City of N.Y, Daniel W. Webster, Garen J. Wintemute, Hemenway D, Kleck G, Magaddino JP, Mayors Against Illegal Guns, Moorhouse JC, U.S. Bur. Alcohol, Tob. Firearms, U.S. Bur. Alcohol, Tob. Firearms, U.S. Bur. Alcohol, Tob. Firearms, Vigdor ER, Webster DW, Wintemute GJ, Wright MA   +16 more
core   +1 more source

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

PLoS ONE, 2018
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown.
M. Feitosa, A. Kraja, D. Chasman, Y. Sung, T. Winkler, I. Ntalla, Xiuqing Guo, N. Franceschini, Ching-Yu Cheng, X. Sim, D. Vojinovic, J. Marten, S. Musani, Changwei Li, A. Bentley, Michael R. Brown, K. Schwander, Melissa A. Richard, R. Noordam, H. Aschard, Traci M. Bartz, L. Bielak, R. Dorajoo, Virginia Fisher, F. Hartwig, A. Horimoto, K. Lohman, A. Manning, T. Rankinen, A. Smith, S. Tajuddin, M. Wojczynski, Maris Alver, M. Boissel, Q. Cai, A. Campbell, Jin-Fang Chai, Xu Chen, J. Divers, Chuan Gao, A. Goel, Y. Hagemeijer, S. Harris, M. He, F. Hsu, A. Jackson, M. Kähönen, A. Kasturiratne, P. Komulainen, Brigitte Kühnel, F. Laguzzi, J. Luan, N. Matoba, I. Nolte, S. Padmanabhan, Muhammad B. Riaz, R. Rueedi, A. Robino, M. A. Said, R. Scott, T. Sofer, A. Stančáková, F. Takeuchi, B. Tayo, Peter J. van der Most, T. Varga, V. Vitart, Yajuan Wang, E. Ware, H. Warren, S. Weiss, W. Wen, L. Yanek, Weihua Zhang, Jinghua Zhao, S. Afaq, N. Amin, M. Amini, D. Arking, T. Aung, E. Boerwinkle, I. Borecki, U. Broeckel, Morris J. Brown, M. Brumat, G. Burke, M. Canouil, A. Chakravarti, S. Charumathi, Y. Ida Chen, J. Connell, A. Correa, L. de las Fuentes, R. de Mutsert, H. J. de Silva, Xuan Deng, Jingzhong Ding, Qing Duan, C. Eaton, G. Ehret, R. N. Eppinga, E. Evangelou, J. Faul, S. Felix, N. Forouhi, T. Forrester, O. Franco, Y. Friedlander, I. Gandin, He Gao, M. Ghanbari, B. Gigante, C. Gu, D. Gu, S. Hagenaars, G. Hallmans, T. Harris, Jiang He, S. Heikkinen, C. Heng, M. Hirata, B. Howard, M. Ikram, U. John, T. Katsuya, C. Khor, T. Kilpeläinen, W. Koh, J. Krieger, S. Kritchevsky, M. Kubo, J. Kuusisto, T. Lakka, C. Langefeld, C. Langenberg, L. Launer, B. Lehne, C. Lewis, Yize Li, Shiow J. Lin, Jianjun Liu, Jingmin Liu, M. Loh, T. Louie, R. Mägi, C. McKenzie, T. Meitinger, A. Metspalu, Y. Milaneschi, L. Milani, K. Mohlke, Y. Momozawa, M. Nalls, C. Nelson, N. Sotoodehnia, J. Norris, Jeffery R O'connell, Nicholette D. Palmer, T. Perls, N. Pedersen, A. Peters, P. Peyser, N. Poulter, L. Raffel, O. Raitakari, Kathryn Roll, L. Rose, F. Rosendaal, J. Rotter, C. Schmidt, P. Schreiner, N. Schupf, W. Scott, P. Sever, Yuan Shi, S. Sidney, M. Sims, C. Sitlani, Jennifer A. Smith, H. Snieder, J. Starr, K. Strauch, H. Stringham, N. Tan, Hua Tang, K. Taylor, Y. Teo, Y. Tham, S. Turner, A. Uitterlinden, P. Vollenweider, M. Waldenberger, Lihua Wang, Y. X. Wang, W. Wei, Christine A. Williams, Jie Yao, Caizheng Yu, Jian-Min Yuan, Wei Zhao, A. Zonderman, D. Becker, M. Boehnke, D. Bowden, J. Chambers, I. Deary, T. Esko, M. Farrall, P. Franks, B. Freedman, P. Froguel, P. Gasparini, C. Gieger, J. Jonas, Y. Kamatani, N. Kato, J. Kooner, Z. Kutalik, M. Laakso, C. Laurie, K. Leander, T. Lehtimäki, Lifelines Cohort Study, P. Magnusson, A. Oldehinkel, B. Penninx, O. Polašek, D. Porteous, R. Rauramaa, N. Samani, J. Scott, X. Shu, P. van der Harst, L. Wagenknecht, N. Wareham, H. Watkins, D. Weir, A. R. Wickremasinghe, Tangchun Wu, W. Zheng, C. Bouchard, K. Christensen, M. Evans, V. Gudnason, B. Horta, S. Kardia, Yongmei Liu, A. Pereira, B. Psaty, P. Ridker, R. V. van Dam, W. Gauderman, Xiaofeng Zhu, D. Mook-Kanamori, M. Fornage, C. Rotimi, L. Cupples, T. Kelly, E. Fox, C. Hayward, C. V. van Duijn, E. Tai, T. Wong, C. Kooperberg, W. Palmas, K. Rice, A. Morrison, P. Elliott, M. Caulfield, P. Munroe, D. Rao, M. Province, D. Levy   +272 more
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

The Community-Based Medication-First program for opioid use disorder: a hybrid implementation study protocol of a rapid access to buprenorphine program in Washington State

Addiction Science & Clinical Practice, 2022
Background Opioid use disorder (OUD) is a serious health condition that is effectively treated with buprenorphine. However, only a minority of people with OUD are able to access buprenorphine.
Caleb J. Banta-Green, Mandy D. Owens, Jason R. Williams, Jeanne M. Sears, Anthony S. Floyd, Wendy Williams-Gilbert, Susan Kingston   +6 more
doaj   +1 more source

Britain's alcohol problem and what the UK government is (and is not) doing about it [PDF]

, 2006
Britain is currently experiencing a serious alcohol problem, as shown particularly by a steep increase in rates of liver cirrhosis mortality and by widespread alcohol-related disorder and harm among young people.
Heather, Nick
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Public Health Considerations and the Culture of Alcohol in Vietnam [PDF]

, 2016
The problem of alcohol in Vietnam is interesting when considering the culture surrounding alcohol throughout the country, particularly amongst men. In 2010, Vietnamese men drank 12.1 liters of pure alcohol per capita, while women drank only 0.2 liters ...
Baquet, Daniel
core   +1 more source