Results 181 to 190 of about 1,349,906 (378)

On the Effects of Some Heterocyclic Compounds on the Enzymic Activity of Liver Alcohol Dehydrogenase. [PDF]

open access: bronze, 1969
Hugo Theorell   +7 more
openalex   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

open access: yesAnimal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao   +12 more
wiley   +1 more source

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

open access: yesHepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres   +21 more
wiley   +1 more source

Optimizing jojoba oil methanolysis of cis‐13‐docosenol fatty alcohol to unveil its immunomodulatory potential: a circular biorefinery perspective

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The sustainable production of jojoba oil derivatives depends on research and development focused on eco‐friendly valorization processes. This study establishes optimal conditions for converting jojoba oil into jojobyl alcohols, which is a key step in realizing its economic potential.
Laura Mendoza‐García   +3 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

Increased alcohol dehydrogenase 1 activity promotes longevity. [PDF]

open access: yesCurr Biol, 2023
Ghaddar A   +10 more
europepmc   +1 more source

Assessment of Anticancer Effects of Aloe vera on 3D Liver Tumor Spheroids in a Microfluidic Platform

open access: yesBiotechnology and Bioengineering, EarlyView.
The comparative effects of Doxorubicin and Aloe vera on HepG2 spheroids grown in a microfluidic device are illustrated in the graphical abstract. In the upper panel, red markers indicate that Doxorubicin treatment primarily induces necrosis in the spheroids.
Atakan Tevlek   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy