Results 11 to 20 of about 1,338,228 (382)
Antioxidants, 2022 Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still not fully elucidated.
Evangelia Eirini Tsermpini +2 more
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Alcohol dehydrogenase and aldehyde dehydrogenase in malignant neoplasms [PDF]
Clinical and Experimental Medicine, 2016 According to International Agency for Research on Cancer, ethanol and acetaldehyde belong to group 1 of human carcinogens. The accurate mechanism by which alcohol consumption enhances carcinogenesis is still unexplained. Alcohol is oxidized primarily by alcohol dehydrogenase (ADH) to acetaldehyde, a substance capable of initiating carcinogenesis by ...
Maciej Szmitkowski, Karolina Orywal
openaire +4 more sources
Immobilization and stabilization of alcohol dehydrogenase on polyvinyl alcohol fibre
Biotechnology Reports, 2018 A polyvinyl alcohol (PVA) fibrous carrier has been chemically modified for the immobilization of yeast alcohol dehydrogenase (ADH) with an aim to increase its stability over a wide pH range, prolong its activity upon storage, and enhance its reusability.
Priydarshani Shinde +4 more
doaj +2 more sources
Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review [PDF]
Alcoholism: Clinical and Experimental Research, 2018 Alcohol use disorders (AUDs) are complex traits, meaning that variations in many genes contribute to the risk, as does the environment. Although the total genetic contribution to risk is substantial, most individual variations make only very small contributions. By far the strongest contributors are functional variations in 2 genes involved in alcohol (
Howard J. Edenberg +1 more
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Enzymatic properties of alcohol dehydrogenase PedE_M.s. derived from Methylopila sp. M107 and its broad metal selectivity. [PDF]
Front Microbiol, 2023 As an important metabolic enzyme in methylotrophs, pyrroloquinoline quinone (PQQ)-dependent alcohol dehydrogenases play significant roles in the global carbon and nitrogen cycles. In this article, a calcium (Ca2+)-dependent alcohol dehydrogenase PedE_M.s.
Xiao Y +7 more
europepmc +2 more sources
Biomedicines, 2020 Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase.
Yanchao Jiang +5 more
semanticscholar +1 more source
The effect of low concentrations of ethanol on gastric adenocarcinoma cell lines [PDF]
Archives of Biological Sciences, 2014 Chronic alcohol consumption has been identified as a significant risk factor for cancer in humans. The aim of the study was to analyze the influence of low concentrations of ethanol on gastric adenocarcinoma cell viability, apoptosis, and ...
Wu Lingjiao +3 more
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The effect of low concentrations of ethanol on gastric adenocarcinoma cell lines [PDF]
Archives of Biological Sciences, 2013 Chronic alcohol consumption was identified as a significant risk factor for cancer in humans. The aim of the study was to analyze the influence of low concentrations of ethanol on gastric adenocarcinoma cell viability, apoptosis, and changes in the ...
Wu Lingjiao +3 more
doaj +1 more source
Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice. [PDF]
PLoS ONE, 2016 Why only a subpopulation (about 15%) of humans develops liver cirrhosis due to alcohol is a critical as yet unanswered question. Liver-specific depletion of augmenter of liver regeneration (ALR) protein in mice causes robust steatosis and hepatocyte ...
Sudhir Kumar +3 more
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Alcohol Dehydrogenase of a Novel Algae Fermentation Strain Meyerozyma guilliermondii [PDF]
Chemical and Biochemical Engineering Quarterly, 2018 The production of bioethanol from algae has attracted wide attention in the field of energy. A novel algae fermentation strain, Meyerozyma guilliermondii, can produce alginate mlyase and alcohol dehydrogenase (ADH) at the same time.
W. Zhang +4 more
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