Results 211 to 220 of about 210,614 (338)

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

open access: yesChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

open access: yesLiver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono   +8 more
wiley   +1 more source

Inhibition of the clathrin terminal domain – amphiphysin protein‐protein interaction. Probing the Pitstop® 2 aromatic moiety.

open access: yesChemMedChem, Accepted Article.
Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)‐4‐oxo‐4,5‐dihydrothiazol‐2‐yl)naphthalene‐1‐sulfonamide (1), inhibits the clathrin terminal domain‐ amphiphysin interaction (NTD‐PPI) and has been widely used to investigate endocytosis. In this work we report on the synthesis of 56 novel Pitstop 2 analogues via four discrete focused libraries.
Kate Prichard   +10 more
wiley   +1 more source

Heterogeneity of Horse Liver Alcohol Dehydrogenase [PDF]

open access: bronze, 1970
Ursula M. Lutstorf   +2 more
openalex   +1 more source

Effects of Silver and Mercurials on Yeast Alcohol Dehydrogenase

open access: hybrid, 1960
Philip J. Snodgrass   +2 more
openalex   +1 more source

The Role of Five‐Membered Aromatic Rings Containing N and O in Modulating Bile Acid Receptors: An Overview

open access: yesChemMedChem, Accepted Article.
Over the past decades extensive scientific research in the fields of chemistry and pharmaceutical chemistry has led to the synthesis and study of numerous chemical compounds with diverse therapeutic applications. Many of these compounds feature heterocyclic aromatic structures, including six‐, five‐, and four‐membered rings.
Claudia Finamore   +5 more
wiley   +1 more source

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