Results 221 to 230 of about 210,614 (338)

Changes in Protein Expression of Renal Drug Transporters and Drug‐Metabolizing Enzymes in Autosomal Dominant Polycystic Kidney Disease Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann   +6 more
wiley   +1 more source

Two-Photon Excited Fluorescence of NADH-Alcohol Dehydrogenase Complex in a Mixture with Bacterial Enzymes. [PDF]

open access: yesBiomolecules, 2023
Gorbunova IA   +6 more
europepmc   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang   +6 more
wiley   +1 more source

A Simple Strategy for Co‐Immobilization of NADH‐Dependent Enzymes and NADH for Efficient Biocatalysis in Continuous Flow Reactors

open access: yesChemSusChem, EarlyView.
Polyethylenimine‐modified Cry3Aa‐formate dehydrogenase (FDH)/Cry3Aa‐leucine dehydrogenase (LDH) fusion particles entrapped in agarose beads enables efficient NADH recycling, thereby facilitating the continuous synthesis of chiral intermediates in a flow reactor.
Reza Yekta   +3 more
wiley   +1 more source

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