The role of the gut microbiome in the regulation of high‐altitude adaptation
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang +6 more
wiley +1 more source
Genome-wide identification of alcohol dehydrogenase (ADH) gene family in oilseed rape (Brassica napus L.) and BnADH36 functional verification under salt stress. [PDF]
Zhang H +9 more
europepmc +1 more source
Akermanite scaffolds promote osteogenic differentiation of BMSCs through regulating the PI3K/Akt signaling pathway, and strontium ions enhance the akermanite effects by mediating the cytokine‐cytokine receptor interaction pathway. Thus, the enhancements of osteogenesis in subchondral bone coupled with the chondral‐promoting effects of chondrocytes ...
Bo Li +15 more
wiley +1 more source
Substitution of both histidines in the active site of yeast alcohol dehydrogenase 1 exposes underlying pH dependencies. [PDF]
Jacobi T, Kratzer DA, Plapp BV.
europepmc +1 more source
Cell Toxicity and Autophagy in A549 Cells Treated With Surface‐Functionalized Graphene Derivatives
ABSTRACT Graphene oxide and its derivatives have unique physical and chemical properties with applications in many different fields. However, their biological effects and mechanisms of intracellular toxicity have not been completely clarified. In this study, we investigated the cytotoxic and autophagic activities of graphene oxide and its derivatives ...
Tae Yun Park +6 more
wiley +1 more source
Identification of the Cinnamyl Alcohol Dehydrogenase Gene Family in <i>Brassica</i> U-Triangle Species and Its Potential Roles in Response to Abiotic Stress and Regulation of Seed Coat Color in <i>Brassica napus</i> L. [PDF]
Liu Y +11 more
europepmc +1 more source
A personal 360° view of applications of ‘biomimetic’ molecular recognition
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley +1 more source
Solvent isotope and mutagenesis studies on the proton relay system in yeast alcohol dehydrogenase 1. [PDF]
Plapp BV.
europepmc +1 more source

