Results 61 to 70 of about 1,349,906 (378)
Carriage of rs738409:G in patatin‐like phospholipase domain containing 3 (PNPLA3) is associated with an increased risk for developing alcohol‐related cirrhosis and hepatocellular carcinoma (HCC).
F. Stickel+47 more
semanticscholar +1 more source
An iron‐activated alcohol dehydrogenase [PDF]
An alcohol dehydrogenase isolated from Zymomonas mobilis was found to be activated by ferrous ions but not by zinc, after inactivation with metal‐complexing agents. Cobaltous ions also re‐activated to a lesser extent. It is suggested that in this species the alcohol dehydrogenase naturally contains iron.
openaire +3 more sources
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
New glycosylated zein peptides (GZP) were produced by transglutaminase-induced d-glucosamine conjugation onto zein peptides. GZP’s antagonistic effects on alcohol-induced liver injury in rats were evaluated.
Xiao-jie Wang+4 more
doaj
The Metabolism of Alcohol: Risk and Protective Factors [PDF]
Purpose: Abstract for poster submission to VCU Poster Symposium for Undergraduate Research and Creativity Title: The Metabolism of Alcohol: Risk and Protective Factors Background: In 2002, it was reported by the National Institutes of Health that 60.3 ...
Adkins, Amy+3 more
core +1 more source
Branched chain aldehydes: production and breakdown pathways and relevance for flavour in foods [PDF]
Branched aldehydes, such as 2-methyl propanal and 2- and 3-methyl butanal, are important flavour compounds in many food products, both fermented and non-fermented (heat-treated) products. The production and degradation of these aldehydes from amino acids
Engels, W.J.M., Smit, B.A., Smit, G.
core +2 more sources
Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari+9 more
wiley +1 more source
Chronic alcohol consumption can cause hepatic injury and alcohol-induced toxicities. Extracts from Smilax china root have been widely used in traditional medicine and for their potential pharmacological benefits. We aimed to determine if fermented Smilax
Naila Boby+7 more
doaj +1 more source
Site directed mutagenesis and purification of the cDNA for human class I aldehyde dehydrogenase : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science at Massey University [PDF]
Aldehyde dehydrogenase (ALDH) is a key enzyme of alcohol metabolism, removing acetaldehyde which is formed as a product of the alcohol dehydrogenase reaction.
Wansbrough, Erin M
core
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source