Results 1 to 10 of about 50 (48)
Treatment of alcohol dependence [PDF]
The present review summarizes current research on the management of alcohol dependence, including pharmacotherapy, psychosocial interventions and treatment of alcohol dependence with comorbid psychiatric disorders.Among recent studies, naltrexone has demonstrated the most consistent effect in reducing alcohol consumption in the context of behavioral ...
Manit Srisurapanont+1 more
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Acamprosate for alcohol dependence [PDF]
Alcohol dependence is among the main leading health risk factors in most developed and developing countries. Therapeutic success of psychosocial programs for relapse prevention is moderate, but could potentially be increased by an adjuvant treatment with the glutamate antagonist acamprosate.To determine the effectiveness and tolerability of acamprosate
Rösner, Susanne+5 more
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Gabapentin in Alcohol Dependence [PDF]
Objective: To review the literature related to the use of gabapentin in alcohol dependence following acute alcohol withdrawal. Data Sources: Searches of MEDLINE (1946-January 2015) and Cochrane Database (2005-January 2015) were performed using gabapentin, alcohol, and alcoholism as MeSH terms and keywords.
Morgan D. Greutman+4 more
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Drugs for alcohol dependence [PDF]
There is good evidence for the use of pharmacological treatments to improve outcomes in patients with alcohol use disorders (AUD). The management of acute withdrawal should include a high risk of suspicion for Wernicke–Korsakoff Syndrome, necessitating treatment with parenteral high-potency B vitamins (Pabrinex®).
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Genetics of alcohol dependence [PDF]
Twin, family, and adoption studies have consistently shown that genetic factors play an important role in the pathogenesis of alcohol dependence. Numerous studies have aimed to identify genes that contribute to susceptibility to alcohol dependence. Whole‐genome linkage studies have identified several chromosomal regions that are linked with alcohol ...
Susumu Higuchi, Mitsuru Kimura
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Genetics of alcohol dependence [PDF]
Alcohol dependence (AD), a genetically influenced phenotype, is extremely costly to individuals and to society in the United States and throughout the world, contributing to morbidity and mortality and a host of economic, interpersonal, and societal problems.
Joel Gelernter, Henry R. Kranzler
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Treatment of alcohol dependence
It is important to manage alcohol withdrawal properly. Mismanagement could lead to permanent brain damage or even death. The principles are simple and easily learnt. New pharmacological agents have come into use which helps in maintaining abstinence. Clinicians should update themselves on their use.
Varuni de Silva, Raveen Hanwella
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Pharmacogenetics of Alcohol and Alcohol Dependence Treatment [PDF]
In this article, we review studies of genetic moderators of the response to medications to treat alcohol dependence, the acute response to alcohol, and the response to the psychotherapeutic treatment of heavy drinking. We consider four neurotransmitter systems: opioidergic, dopaminergic, GABAergic, and glutamatergic and focus on one receptor protein in
Henry R. Kranzler, Howard J. Edenberg
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Neuroinflammmation in alcohol dependence [PDF]
Alcohol dependence damages the brain through a multiplicity of factors including thiamine deficiency, liver disease, head injuries, and repeated episodes of alcohol withdrawal. Alcohol withdrawal is a potential opportunity for reducing damage as it is an intensive time of contact between doctors and patients.
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