Results 41 to 50 of about 1,742,228 (306)
Correlations between sex-related hormones, alcohol dependence and alcohol craving
Background: Sex-related differences in the susceptibility, progression, and treatment response in alcohol-dependent subjects have been repeatedly reported.
Winham, Stacey J. +9 more
core +1 more source
Background To describe the prevalence of alcohol dependence and to explore the relationship between alcohol dependence and newly detected hypertension in China.
Ailing Ji +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Center of Alcohol Studies and the JOURNAL OF STUDIES ON ALCOHOL: Celebrating 50 Years
Copy of the article Nathan, P. E. (1989). The Center of Alcohol Studies and the Journal of Studies on Alcohol: celebrating 50 years. Journal of Studies on Alcohol, 50(4), 297–300. https://doi.org/10.15288/jsa.1989.50.297.
Nathan, Peter
core +1 more source
Introduction: Alcohol dependence is an important risk factor for suicidal behaviours. Current data show that between 14 and 43% of alcohol-dependent patients attempt suicide.
Aneta Michalska +6 more
doaj +1 more source
Background: Excessive alcohol use leads to a spectrum of liver disease. While physicians treat liver disease, the cause, i.e. alcohol, often remains untreated.
CS Bharath +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
BackgroundWith the use of ketamine, Glutamate (Glu) system has gradually become the focus of antidepressant effects. N-methyl-D-aspartate receptor (NMDAR), as one of the major ionic glutamate receptors, plays a dominant role in antidepressant effects ...
Zuxing Feng +7 more
doaj +1 more source
Introduction: Delirium tremens (DT) is a life-threatening complication that occurs in 5–33% of patients treated for alcohol withdrawal syndrome. The aim of the present study was to analyse the risk factors for delirium tremens among patients treated for ...
Aneta Michalska +8 more
doaj +1 more source
Pharmacogenetics of Alcohol and Alcohol Dependence Treatment [PDF]
In this article, we review studies of genetic moderators of the response to medications to treat alcohol dependence, the acute response to alcohol, and the response to the psychotherapeutic treatment of heavy drinking. We consider four neurotransmitter systems: opioidergic, dopaminergic, GABAergic, and glutamatergic and focus on one receptor protein in
Henry R, Kranzler, Howard J, Edenberg
openaire +2 more sources

