Results 141 to 150 of about 941,604 (214)
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Journal of Medicinal Chemistry, 1990
Utilisation de cyanamide marque au 15 N et au 13 C pour mettre en evidence l'intermediaire N-hydroxycyanamide donnant par decomposition le nitroxyle (HN=0), inhibiteur de l'aldehyde deshydrogenase (ALDH)
H T, Nagasawa +4 more
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Utilisation de cyanamide marque au 15 N et au 13 C pour mettre en evidence l'intermediaire N-hydroxycyanamide donnant par decomposition le nitroxyle (HN=0), inhibiteur de l'aldehyde deshydrogenase (ALDH)
H T, Nagasawa +4 more
openaire +2 more sources
Cyanide is a product of the catalase-mediated oxidation of the alcohol deterrent agent, cyanamide
Toxicology Letters, 1987Cyanide was detected as a product of cyanamide oxidation by bovine liver catalase in vitro under conditions that also produced an active aldehyde dehydrogenase (AlDH) inhibitor. Cyanide formation was directly related to both cyanamide and catalase concentrations and was also dependent on incubation time. The apparent Km for this reaction was 172 microM.
F N, Shirota +2 more
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Transportation Research Part F: Traffic Psychology and Behaviour, 2021
Abstract Background While attempts to identify the mechanisms to effectively deter drink driving remains a central focus for road safety researchers, scant scientific enquiry has simultaneously examined perceptions of apprehension risk in combination with substance abuse.
James Freeman +4 more
openaire +1 more source
Abstract Background While attempts to identify the mechanisms to effectively deter drink driving remains a central focus for road safety researchers, scant scientific enquiry has simultaneously examined perceptions of apprehension risk in combination with substance abuse.
James Freeman +4 more
openaire +1 more source
Deterrence and prevention of alcohol-impaired driving in Australia, the United States, and Norway
Justice Quarterly, 1990A sample of 4,316 drivers from Norway, the United States, and Australia responded to national surveys probing individual, social, and legal factors that contribute to control of alcohol-impaired driving. These factors are considered within the framework of general deterrence (control in response to a fear of punishment) and general prevention (control ...
Dale E. Berger +4 more
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Evaluation Review, 2011
This article examines alcohol-impaired collision metrics around nine sobriety checkpoint locations in Indianapolis, Indiana, before and after implementation of 22 checkpoints, using a pre/post examination, a pre/post nonequivalent comparison group analysis, and an interrupted time series approach. Traffic safety officials used geographical information
Samuel, Nunn, William, Newby
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This article examines alcohol-impaired collision metrics around nine sobriety checkpoint locations in Indianapolis, Indiana, before and after implementation of 22 checkpoints, using a pre/post examination, a pre/post nonequivalent comparison group analysis, and an interrupted time series approach. Traffic safety officials used geographical information
Samuel, Nunn, William, Newby
openaire +2 more sources
Biochemical Pharmacology, 1998
Nitroxyl, produced in the bioactivation of the alcohol deterrent agent cyanamide, is a potent inhibitor of aldehyde dehydrogenase (AIDH); however, the mechanism of inhibition of AlDH by nitroxyl has not been described previously. Nitroxyl is also generated from Angeli's salt (Na2N2O3) at physiological pH, and, indeed, Angeli's salt inhibited yeast AlDH
E G, DeMaster, B, Redfern, H T, Nagasawa
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Nitroxyl, produced in the bioactivation of the alcohol deterrent agent cyanamide, is a potent inhibitor of aldehyde dehydrogenase (AIDH); however, the mechanism of inhibition of AlDH by nitroxyl has not been described previously. Nitroxyl is also generated from Angeli's salt (Na2N2O3) at physiological pH, and, indeed, Angeli's salt inhibited yeast AlDH
E G, DeMaster, B, Redfern, H T, Nagasawa
openaire +2 more sources
Journal of Medicinal Chemistry, 1986
Cyanamide (H2NC identical to N), a potent aldehyde dehydrogenase (AlDH) inhibitor that is used therapeutically as an alcohol deterrent agent, is known to be rapidly metabolized and excreted in the urine as acetylcyanamide (1). On the basis of our observation that 1 is deacetylated to cyanamide in vivo, albeit very slightly, thereby serving as a ...
C H, Kwon +3 more
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Cyanamide (H2NC identical to N), a potent aldehyde dehydrogenase (AlDH) inhibitor that is used therapeutically as an alcohol deterrent agent, is known to be rapidly metabolized and excreted in the urine as acetylcyanamide (1). On the basis of our observation that 1 is deacetylated to cyanamide in vivo, albeit very slightly, thereby serving as a ...
C H, Kwon +3 more
openaire +2 more sources
Journal of Drug Education, 2009
In the present study we advance previous research in deterrence theory by examining the perceived deterrent effects of a newly instituted dry policy on a college campus. A survey of 500 full-time undergraduate students between the ages of 18 and 26 was conducted 3 months following the ban on alcohol.
Margaret S, Kelley +3 more
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In the present study we advance previous research in deterrence theory by examining the perceived deterrent effects of a newly instituted dry policy on a college campus. A survey of 500 full-time undergraduate students between the ages of 18 and 26 was conducted 3 months following the ban on alcohol.
Margaret S, Kelley +3 more
openaire +2 more sources
Modified Parallel Tracking and Mapping for Augmented Reality as an Alcohol Deterrent
2019Drug addiction among the population is a major social menace. This paper proposes an innovative method to offer a promising deterrent against alcohol abuse using Augmented Reality (AR) as a tool. The proposed method aims at traumatizing an alcoholic person by augmenting multiple multimedia objects in the vicinity of a person.
Prabhanshu Purwar +3 more
openaire +1 more source
Journal of American College Health, 2002
Underage drinking is a major problem at American colleges, but little is known about the extent of alcohol use in different student groups, in different colleges, and in states with different control policies. We used data from the 2001 and 3 previous Harvard School of Public Health College Alcohol Studies that compared responses of underage students ...
Henry, Wechsler +3 more
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Underage drinking is a major problem at American colleges, but little is known about the extent of alcohol use in different student groups, in different colleges, and in states with different control policies. We used data from the 2001 and 3 previous Harvard School of Public Health College Alcohol Studies that compared responses of underage students ...
Henry, Wechsler +3 more
openaire +2 more sources