Results 11 to 20 of about 941,604 (214)

3D printed opioid medicines with alcohol-resistant and abuse-deterrent properties [PDF]

International Journal of Pharmaceutics, 2020
In the past decade, prescriptions for opioid medicines have been exponentially increasing, instigating opioid abuse as a global health crisis associated with high morbidity and mortality. In particular, diversion from the intended mode of opioid administration, such as injecting and snorting the opioid, is a major problem that contributes to this ...
Jun Jie Ong, Atheer Awad, Annalisa Martorana, Simon Gaisford, Edmont Stoyanov, Abdul W. Basit, Alvaro Goyanes   +6 more
openaire   +3 more sources

Adolescent Drug Use in Connecticut Private High Schools: Zero Tolerance, Contextual Peer Influence, and Deterrence Effectiveness

, 2020
After the 1994 Gun-Free School Act, schools expanded the use of zero-tolerance policies with all Connecticut private high schools implementing punitive drug and alcohol policies.
Minjune Song
semanticscholar   +1 more source

Assessment and prediction of spatial patterns of human-elephant conflicts in changing land cover scenarios of a human-dominated landscape in North Bengal.

PLoS ONE, 2019
It is of utmost importance to research on the spatial patterns of human-wildlife conflicts to understand the underlying mechanism of such interactions, i.e. major land use changes and prominent ecological drivers. In the north eastern part of India there
Dipanjan Naha, S Sathyakumar, Suraj Dash, Abhishek Chettri, G S Rawat   +4 more
doaj   +1 more source

Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study

European Neuropsychopharmacology, 2021
Sodium oxybate (SMO) has been approved in Italy and Austria for the maintenance of abstinence in alcohol dependent (AD) patients. Although SMO is well tolerated in AD patients, cases of abuse and misuse have been reported outside the therapeutic setting.
Guiraud J., Addolorato G., Aubin H. -J., Batel P., de Bejczy A., Caputo F., Goudriaan A. E., Gual A., Lesch O., Maremmani I., Perney P., Poulnais R., Raffaillac Q., Soderpalm B., Spanagel R., Walter H., van den Brink W.   +16 more
openaire   +6 more sources

Present and future potential of plant-derived products to control arthropods of veterinary and medical significance [PDF]

, 2014
The use of synthetic pesticides and repellents to target pests of veterinary and medical significance is becoming increasingly problematic. One alternative approach employs the bioactive attributes of plant-derived products (PDPs). These are particularly
Finn, Robert, George, David, Graham, Kirsty, Sparagano, Olivier   +3 more
core   +1 more source

Three-year mortality among alcoholic patients after intensive care: a population-based cohort study

Critical Care, 2012
IntroductionAlcoholic patients comprise a large proportion of patients in intensive care units (ICUs). However, data are limited on the impact of alcoholism on mortality after intensive care.MethodsWe conducted a cohort study among 16,848 first-time ICU ...
S. Christensen, M. B. Johansen, L. Pedersen, R. Jensen, K. Larsen, A. Larsson, E. Tønnesen, C. Christiansen, H. Sørensen   +8 more
semanticscholar   +1 more source

The ‘oldest tricks in the book’ don’t work! Reports of burglary by DUMA detainees in Western Australia [PDF]

, 2014
Explores the methods and motivations of those actively involved in committing burglaries. Foreword Research investigating the methods and motivations of burglars has typically focused on incarcerated offenders. The Australian Institute of Criminology’s
Anthony Scott, Jennifer Fleming, Natalie Gately, Nathalie McGinty   +3 more
core   +1 more source

Assessment of Alcohol-Induced Dose Dumping with a Hydrocodone Bitartrate Extended-Release Tablet Formulated with CIMA® Abuse Deterrence Technology [PDF]

Clinical Drug Investigation, 2015
Greater drug content requirements for extended-release (ER) opioids necessitate greater protection against dose dumping. Hydrocodone ER employs the CIMA(®) Abuse-Deterrence Technology platform, which provides resistance against rapid release of the active moiety when the tablet is manipulated or taken with alcohol.Assess effects of alcohol on ...
Darwish, Mona, Bond, Mary, Yang, Ronghua, Tracewell, William, Robertson, Philmore   +4 more
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Undergraduate Students’ Perception of the Consequences of Alcohol Consumption [PDF]

, 2017
Due to the high-risk outcomes of college drinking, much attention and research has focused on the issues of binge drinking, alcohol overconsumption, and the experience of adverse consequences due to drinking on college campuses.
Giglio, Elaine
core   +1 more source