Results 71 to 80 of about 650,959 (208)

Polyphyllin I Alleviates Alcoholic Liver Disease via Modulation of the Phosphodiesterase 6D–Cyclic Guanosine Monophosphate–Protein Kinase G Axis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alcoholic liver disease (ALD) is a multifaceted disorder in which oxidative injury, iron‐dependent ferroptosis, steatosis, and inflammation are closely intertwined. Consequently, therapeutic strategies targeting a single pathway often produce limited clinical benefits.
Hongyan Feng   +7 more
wiley   +1 more source

"What are you meant to do when you see it everywhere?": Young people, alcohol packaging and digital media [PDF]

open access: yes, 2014
The consumption of alcohol plays an important part in the way in which people create identities and live their social lives. Alcohol brands become embedded in everyday life through marketing practices, and this is amplified by an increase in new ...
Purves, Richard   +2 more
core  

Alcohol and aggression

open access: yes, 1945
Chapter in the volume entitled "Alcohol, science and society. Twenty-nine lectures with discussions as given at the Yale Summer School of Alcohol Studies.

core   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

The metabolism of alcohol

open access: yes, 1945
Chapter in the volume entitled "Alcohol, science and society. Twenty-nine lectures with discussions as given at the Yale Summer School of Alcohol Studies.

core   +1 more source

Similarity of Escherichia coli propanediol oxidoreductase (fucO product) and an unusual alcohol dehydrogenase from Zymomonas mobilis and Saccharomyces cerevisiae [PDF]

open access: yesJournal of Bacteriology, 1989
The gene that encodes 1,2-propanediol oxidoreductase (fucO) from Escherichia coli was sequenced. The reading frame specified a protein of 383 amino acids (including the N-terminal methionine), with an aggregate molecular weight of 40,642. The induction of fucO transcription, which occurred in the presence of fucose, was confirmed by Northern blot ...
T, Conway, L O, Ingram
openaire   +2 more sources

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

open access: yesCell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang   +11 more
wiley   +1 more source

Cover of Alcohol Education Materials

open access: yes, 1975
Cover of the publication Alcohol education materials: an annotated bibliography by Gail G. Milgram published by the Publications Division, Rutgers Center of Alcohol Studies in 1975.Source: Alcohol education materials: an annotated bibliography by Gail G.

core   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination

open access: yesThe FEBS Journal, EarlyView.
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam   +6 more
wiley   +1 more source

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