GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence. [PDF]
The present paper summarizes the preclinical and clinical studies conducted to define the "anti-alcohol" pharmacological profile of the prototypic GABAB receptor agonist, baclofen, and its therapeutic potential for treatment of alcohol use disorder (AUD).
Agabio R, Colombo G
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Impulsivity in Alcohol Use Disorder: A Multidimensional Perspective
Impulsivity is a key construct in the development, maintenance, and escalation of drinking behavior, ulti- mately leading to alcohol use disorder. Because impulsivity is a multidimensional construct and has many ways of measurement, it is difficult to ...
Müge Bozkurt, Cüneyt Evren
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The SyBil-AA real-time fMRI neurofeedback study: protocol of a single-blind randomized controlled trial in alcohol use disorder [PDF]
Background: Alcohol Use Disorder is a highly prevalent mental disorder which puts a severe burden on individuals, families, and society. The treatment of Alcohol Use Disorder is challenging and novel and innovative treatment approaches are needed to ...
Bahs, Nathalie +8 more
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David Bergman,1 Hannes Hagström,2– 4 Andrea Johansson Capusan,5,6 Karl Mårild,7,8 Fredrik Nyberg,9 Kristina Sundquist,10 Jonas F Ludvigsson1,11– 13 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet ...
Bergman D +6 more
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Identifying Early Warning Signs: Addressing Youth Substance Use [PDF]
Of high school students 35 percent indicate they are current drinkers, 20 percent are binge drinkers, and 24 percent use marijuana. By the time they are seniors more than 20 percent will have used a prescription drug for a nonmedical purpose.
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Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders [PDF]
BACKGROUND: The psychological outcomes that accompany smoking cessation are not yet conclusive but positive outcomes could help to persuade quitting.
Bierut, L. J +8 more
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Attachment and emotion regulation in substance addictions and behavioral addictions [PDF]
Background Risky behaviors have been related to emotional regulation and attachment, which may constitute risk factors for developing an addictive behavior. However, there may also be differences between substance and non-substance-related addictions.
Estévez, A +4 more
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Borderline personality disorder and substance use disorders: an updated review
For decades, clinicians and researchers have recognized that borderline personality disorder (BPD) and substance use disorders (SUDs) are often diagnosed within the same person (e.g., (Gunderson JG.
Timothy J. Trull +5 more
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Alcohol use disorder (AUD) affects one in ten Americans. As one of the largest payers of AUD treatment in the United States, Medicaid managed care plays a key role in facilitating access to AUD treatment services and medications. However, little is known
Miguel Antonio Garcia Estrada +10 more
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Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala. [PDF]
Behavioral and clinical studies suggest a critical role of substance P (SP)/neurokinin-1 receptor (NK-1R) signaling in alcohol dependence. Here, we examined regulation of GABA transmission in the medial subdivision of the central amygdala (CeM) by the SP/
Hnasko, TS +3 more
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