Results 101 to 110 of about 872,006 (287)

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

A behavioural and electrophysiological study of factors involved in the relationship between stress and alcohol dependence [PDF]

open access: yes, 2001
Alcohol dependence causes disruption to both work and family life and the associated costs are £150+ million in the UK alone. Stressful life events play a role in initiation of uncontrolled (dependent) drinking and can precipitate relapse to high ethanol
Holt, Jonathon
core  

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv   +16 more
wiley   +1 more source

Anxiety about going back to work might actually be 'alcohol withdrawal symptoms', claims expert.

open access: yes, 2019
New Year revellers who feel anxious about returning to work after binge-drinking during the festive season may actually be suffering from alcohol withdrawal symptoms, according to a liver expert.....

core  

Ethanol Infusion for Alcohol Withdrawal Prophylaxis Does Not Cause Intoxication

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2016
Objective: Alcohol Withdrawal Syndrome (AWS) remains a common problem, especially in trauma and surgical patients. An intravenous ethanol infusion protocol was developed at this institution and previously validated for AWS prophylaxis.
Robert Dillard   +4 more
doaj  

Benzodiazepines for alcohol withdrawal

open access: yes, 2005
Alcohol withdrawal syndrome is a cluster of symptoms that occurs in alcohol-dependent people after cessation or reduction in alcohol use. This systematic review focuses on the evidence of benzodiazepines' use in the treatment of alcohol withdrawal symptoms.To evaluate the effectiveness and safety of benzodiazepines in the treatment of alcohol ...
Ntais, C.   +3 more
openaire   +3 more sources

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Patterns of alcohol policy enforcement activities among local law enforcement agencies: A latent class analysis

open access: yes, 2015
Aims: We assessed levels and patterns of alcohol policy enforcement activities among U.S. local law enforcement agencies. Design/Setting/Participants: We conducted a cross-sectional survey of a representative sample of 1,631 local law enforcement ...
Jones-Webb, Rhonda   +5 more
core   +1 more source

A case of a patient requiring medically supervised withdrawal after ingestion of witch hazel toner as a surrogate alcohol

open access: yesClinical Case Reports
Key Clinical Message Standardized alcohol withdrawal treatments, such as the phenobarbital taper protocol, are effective in the management of alcohol withdrawal syndromes associated with surrogate alcohols including witch hazel toner.
Kayley E. Anderson, Alëna A. Balasanova
doaj   +1 more source

Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates

open access: yesAdvanced Science, EarlyView.
Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta   +3 more
wiley   +1 more source

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