Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan +6 more
wiley +1 more source
Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women
ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan +4 more
wiley +1 more source
The Hidden Dangers of Gabapentinoids in Older Adults: From Accelerated Cognitive Decline to Withdrawal-Induced Neurotoxicity. [PDF]
Nagamine T.
europepmc +1 more source
Abstract Objective To evaluate the association between gender‐based violence (GBV) assessed in early pregnancy and adverse perinatal outcomes using relative and absolute effect measures in an urban low‐ and middle‐income setting. Methods We conducted a prospective cohort study including 3890 singleton pregnancies recruited from two public healthcare ...
Elsa Romelia Moreno‐Verduzco +6 more
wiley +1 more source
The patterns of relapse and abstinence: using machine learning to identify a multidimensional signature of long-term outcome after inpatient alcohol withdrawal treatment. [PDF]
Raabe FJ +10 more
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Assessing the role of Subacute Encephalopathy with Seizures in Alcoholics (SESA) syndrome in the development of status epilepticus: a case report and systematic review with individual patients' analysis. [PDF]
Dasara M +7 more
europepmc +1 more source
Adolescent Withdrawn/Depressed Symptoms: A Pathway From Early Adversity to Later Marijuana Use
ABSTRACT Introduction Adverse childhood experiences (ACEs) are robust predictors of marijuana use, yet the developmental mechanisms remain unclear. Building on prior cross‐sectional studies using broad internalizing composites, this study prospectively distinguishes withdrawn/depressed from anxious/depressed symptoms as candidate mediators across ...
Mahsa P. Yousefkhani +2 more
wiley +1 more source
Orthopaedic Trauma in Patients with Documented Alcohol Use: Injury Mechanisms, Clinical Characteristics, and Geriatric Vulnerability. [PDF]
Sirbu I +11 more
europepmc +1 more source

