Results 211 to 220 of about 868,733 (270)

Measuring Treatment Effectiveness in Real‐World Substance Use Care: A Community‐Based Program Evaluation

open access: yesJournal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study reports findings from a community‐based program evaluation examining treatment effectiveness in a real‐world outpatient substance use care setting. Using a within‐program pre–post design, changes in alcohol and drug use were assessed among clients receiving intensive outpatient services.
Jessie A. Brown   +3 more
wiley   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü   +3 more
wiley   +1 more source

The Positive and Adverse Childhood Experiences (PACE) Framework for Counseling Youths

open access: yesJournal of Counseling &Development, EarlyView.
ABSTRACT Youth mental and behavioral health are significantly shaped by both adverse childhood experiences (ACEs) and positive childhood experiences (PCEs). Yet, counseling scholarship and training often address these domains separately, limiting their translation to counseling practice.
Isak Kim, Jaeyoung Kim, Gahyun Park
wiley   +1 more source

Compare Serum VCAM‐1, NSE, Procalcitonin in Predict Sepsis Induced Encephalopathy in Septic Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum VCAM‐1 is associated with septic encephalopathy in the first 7 days of sepsis. NSE and procalcitonin were not associated with septic encephalopathy. ABSTRACT Background Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Increased concentration of Vascular Cell Adhesion Molecule 1 (VCAM‐1) is associated with SAE in a
Chun‐Fu Lin   +2 more
wiley   +1 more source

Longitudinal Study of Plasma NFL and GFAP as Biomarkers of Alcohol Withdrawal-Associated Brain Injury. [PDF]

open access: yesAddict Biol
Clergue-Duval V   +14 more
europepmc   +1 more source

Reward Deficits in Co‐Occurring Social Anxiety and Depression: The Roles of Anhedonia, Boredom, Loneliness, and COVID‐19 Social Restriction

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Prior research points toward reward deficits as crucial to the link between social anxiety disorder and major depressive disorder. However, studies have not explored specific types of reward deficits or how social‐environmental factors may impact them. The current study examined whether the indirect effects of three reward deficits (anhedonia,
Nathan M. Hager   +4 more
wiley   +1 more source

Increased alcohol drinking and seizure susceptibility in female humanized ApoE4 knockin rats. [PDF]

open access: yesPhysiol Behav
Choi CY   +11 more
europepmc   +1 more source

Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities

open access: yesJCPP Advances, EarlyView.
Abstract Background Contemporary classification systems differ in their conceptualization of ADHD as either an externalizing or neurodevelopmental condition, with both perspectives promoting the common cause model as an explanation of ADHD's comorbidity.
Zheyue Peng, Ashley L. Watts
wiley   +1 more source

Evaluation of 6‐Month Knowledge Retention and Satisfaction After Pedagogical Escape Games in Dentistry

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose To evaluate 6‐month knowledge retention and long‐term satisfaction after two pedagogical escape games (PEGs) addressing foundational (3D printing) and clinical (pediatric dentistry) content in a dental curriculum. Methods In this monocentric serial cross‐sectional study, immediate post‑PEG knowledge was assessed in fifth‑year dental ...
Lina Grich   +8 more
wiley   +1 more source

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