Results 71 to 80 of about 658,178 (349)
Definitions, 2020 L iver disease accounts for 2% of deaths and more than 1% of health care spending in the United States. Nearly half of these deaths and costs are attributed to alcohol-related liver disease.
E. Ellis, D. Adler
semanticscholar +1 more source
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
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Attacking the public health crisis of hepatocellular carcinoma at its roots
Hepatology, EarlyView., 2022 Abstract As the third most common cause of cancer‐related death worldwide with significant mortality rates in the United States, hepatocellular carcinoma has strong association with cirrhosis and chronic hepatitis B virus (HBV) with a growing at‐risk population from the rise in chronic liver disease from alcohol use and nonalcoholic fatty liver disease.
Hannah M. Lee +3 more
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Angiogenesis in alcoholic steatohepatitis, nonalcoholic steatohepatitis and hepatitis C virus infection (immunohistochemical study) [PDF]
Морфологія, 2013 Background. Angiogenesis together with fibrogenesis and regeneration is an important mechanism of tissue reorganization in chronic liver diseases.
Gavrilyuk O.M.
doaj
Canadian Journal of Gastroenterology, 1995 Corticosteroid therapy for acute alcoholic hepatitis has been demonstrated to enhance survival in patients who are encephalopathic, and who do not have renal failure or gastrointestinal bleeding.
Vitor Arantes +4 more
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Role of liver transplantation in severe alcoholic hepatitis [PDF]
Clinical and Molecular Hepatology, 2018 Severe alcoholic hepatitis has very high short term mortality and corticosteroids have been the mainstay of treatment for decades. Patients with Lille score >0.45 are considered non-responders to steroids and have poor outcome.
Ravi Daswani +5 more
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Swiss Medical Weekly, 2021 BACKGROUND AND AIM Acute decompensation and death have been observed in patients with acute hepatitis E virus (HEV) infection and preexisting liver cirrhosis.
Joana Vieira Barbosa +16 more
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Management of alcoholic hepatitis [PDF]
Clinical Medicine, 2001 It is estimated that there are 8,500-7,000 deaths per year from alcoholic hepatitis and/or cirrhosis in the UK. There is evidence of alcoholic hepatitis on liver biopsy in 30-60% of inpatients with alcoholic liver disease. Many patients presenting with alcoholic hepatitis also have established cirrhosis at the time of diagnosis.
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The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
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Health disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
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