Results 211 to 220 of about 387,299 (303)

Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by scRNAseq Analysis. [PDF]

MedComm (2020)
Perumalsamy H, Park S, Kim JE, Xiao X, Kim HY, Jun DW, Yoon TH.   +6 more
europepmc   +1 more source

Alcohol‐Associated Pancreatitis Confers Higher Risk of Advanced Liver Disease Than Alcohol Withdrawal Syndrome

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Alcohol‐associated liver disease frequently presents late as decompensated cirrhosis, representing a missed opportunity for intervention. Extrahepatic alcohol‐related presentations requiring acute care, such as alcohol‐associated pancreatitis and alcohol withdrawal syndrome, may identify heavy drinkers at varying risk for ...
Butros Fakhoury, Leandro Sierra, Krishan Patel, Hyundam Gu, Luis Antonio Díaz, Juan Pablo Arab   +5 more
wiley   +1 more source

Tofogliflozin attenuates liver steatosis and fibrosis in non-diabetic non-alcoholic steatohepatitis mice. [PDF]

BMC Gastroenterol
Ozono Y, Kawakami H, Hatada H, Uchiyama N, Ogawa S, Uchida K, Tamura H, Komaki Y, Nakamura K, Iwakiri H, Hasuike S, Nagata K.   +11 more
europepmc   +1 more source

Association of Aspirin With Improved Clinical Outcomes and Survival in Patients With Compensated Cirrhosis: A Propensity Score‐Matched Study of 25 782 Individuals

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Pharmacologic therapies to prevent decompensation in cirrhosis remain limited. Aim To evaluate the association between aspirin use and cirrhosis‐related outcomes and mortality. Methods This retrospective cohort study utilized deidentified electronic health records from a global federated network (January 2013–July 2025). Adults with
Shahem Abbarh, Bisher Sawaf, Tiago Lemos Cerqueira, Hagen B. Huttner, Annahita Sedghi, Norma J. Diel, Timo Siepmann   +6 more
wiley   +1 more source

A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities. [PDF]

Front Immunol
Gao W, Lin Z, Bao Y, Liu M, Ma G, Chen X, Yu S, Zeng Y.   +7 more
europepmc   +1 more source

Hypocholesterolemia in liver and cardiovascular disease: Friend or foe?

Journal of Internal Medicine, EarlyView.
Abstract Hypocholesterolemia is perceived as benign given its association with lower cardiovascular risk. However, genetic and epidemiological evidence indicates that persistently low levels of low‐density lipoprotein cholesterol (LDL‐C) and apolipoprotein B (ApoB) arise from distinct biological mechanisms with different hepatic implications ...
Valentina Flagiello, Emelie Barreby, Umberto Vespasiani‐Gentilucci, Stefano Romeo   +3 more
wiley   +1 more source

Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis. [PDF]

World J Hepatol
Singh MM, Shah A, Rajak S, Chaturvedi CP, Sinha RA.   +4 more
europepmc   +1 more source

Association of GLP‐1 Receptor Agonists With Gastrointestinal and Liver Outcomes in Adults With Type 2 Diabetes: A Target Trial Emulation Study

Diabetes, Obesity and Metabolism, EarlyView.
Dazheng Zhang, Ying Lu, Xinyao Jian, Haoyuan Wang, Jacquelyn Hatch‐Stein, Ronen Stein, Jennifer Panganiban, Yong Chen   +7 more
wiley   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Correction: Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice. [PDF]

Lipids Health Dis
Nan Y, Wang R, Zhao S, Han F, Wu WJ, Kong L, Fu N, Kong L, Yu J.   +8 more
europepmc   +1 more source